| Title: |
The peripartum viral load cascade and outcomes of infants exposed to HIV in Lesotho |
| Authors: |
Haenggi, Kathrin; Mokebe, Moleboheng; Motaboli, Lipontso; Chakela, Makobefo G.; Kao, Mpho; Kopo, Mathebe; Ayakaka, Irene; Nyakane, Morongoe; Tarumbiswa, Tapiwa; Labhardt, Niklaus D.; Brown, Jennifer A.; Tschumi, Nadine |
| Contributors: |
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Fondation Botnar |
| Source: |
HIV Medicine ; ISSN 1464-2662 1468-1293 |
| Publisher Information: |
Wiley |
| Publication Year: |
2025 |
| Collection: |
Wiley Online Library (Open Access Articles via Crossref) |
| Description: |
Objectives This study describes the peripartum viral load (VL) monitoring cascade among individuals initiating antiretroviral therapy (ART) before delivery, as well as HIV testing, prophylaxis and outcomes of their infants in routine care in Lesotho, southern Africa. Methods Data from medical charts review of paper‐based registers at 20 healthcare facilities in two districts of Lesotho were combined with data from the Viral Load Cohort North‐East Lesotho (VICONEL). We included people with HIV who attended their first antenatal care visit at a participating healthcare facility after 31 December 2019, had a delivery date before 1 January 2022 and initiated dolutegravir‐based ART before delivery, as well as their infants. Results A total of 353 pregnant people with HIV and 357 infants exposed to HIV were recorded. Among 17/353 (5%) with an initial VL ≥1000 copies/mL, a timely (within 4 months) follow‐up VL was provided for 4/17 (24%). Among 233/353 (66%) with an initial VL |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1111/hiv.70082 |
| Availability: |
https://doi.org/10.1111/hiv.70082; https://onlinelibrary.wiley.com/doi/pdf/10.1111/hiv.70082 |
| Rights: |
http://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.3E9ED3C9 |
| Database: |
BASE |