| Title: |
Scanning point terahertz source microscopy of unstained comedo ductal carcinoma in situ |
| Authors: |
OKADA, Kosuke; CASSAR, Quentin; MURAKAMI, Hironaru; MACGROGAN, Gaëtan; GUILLET, Jean Paul; MOUNAIX, Patrick; TONOUCHI, Masayoshi; SERITA, Kazunori |
| Publication Year: |
2022 |
| Subject Terms: |
Sciences de l'ingénieur [physics]/Optique / photonique |
| Description: |
Terahertz imaging is an emerging candidate to diagnose breast cancers in a labelfree manner. However, detailed terahertz analysis of early stage breast cancers is difficult to achieve owing to its low spatial resolution. In this study, utilizing a probe-less terahertz near-field microscope named scanning point terahertz source microscope, we visualize an unstained comedo ductal-carcinoma-in-situ including an architectural structure (comedo necrosis) measuring ∼ϕ500 μm, which is known as highly-malignant early-stage breast cancer, in terahertz images for the first time. The outcome is a critical step toward the label-free diagnosis of single early stage cancer lesions with terahertz waves. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1364/OPTCON.448444 |
| Availability: |
https://oskar-bordeaux.fr/handle/20.500.12278/140167; https://hdl.handle.net/20.500.12278/140167; https://doi.org/10.1364/OPTCON.448444 |
| Rights: |
Attribution 3.0 United States ; open ; http://creativecommons.org/licenses/by/3.0/us/ ; CC BY |
| Accession Number: |
edsbas.3EB6FF7F |
| Database: |
BASE |