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‘Hitting a brick wall’—the importance of careful pacemaker programming

Title: ‘Hitting a brick wall’—the importance of careful pacemaker programming
Authors: Gupta, Ankit; Cole, Charlotte; Straw, Sam; Kamalathasan, Stephe; Gierula, John
Source: Oxford Medical Case Reports ; volume 2025, issue 12 ; ISSN 2053-8855
Publisher Information: Oxford University Press (OUP)
Publication Year: 2025
Description: Background Pacemakers attempt to accurately mirror normal physiology; however, even normal pacemaker functionality can have undesirable effects. Case Summary A 59-year-old male with a background including heart failure, presented with symptoms of ‘hitting a brick wall’ during exertion, years following the implantation of a biventricular pacemaker for third-degree atrioventricular block. He was extensively evaluated, with cardiopulmonary exercise testing and simultaneous device interrogation. After reaching a heart rate of 140 beats/minute, continued exercise resulted in Wenckebach phenomenon and progression to sustained 2:1 atrioventricular block with immediate reductions in oxygen consumption. Ultimately, the aetiology was attributed to upper rate behaviour, rather than the progression of heart failure, and resolved with simple device reprogramming. Discussion Cardiopulmonary exercise testing is an invaluable tool when evaluating patients who present with cardiovascular symptoms. Device reprogramming is often required, including the use of rate-response algorithms where appropriate. Personalisation is key, with programming tailored to the individual’s physiology.
Document Type: article in journal/newspaper
Language: English
DOI: 10.1093/omcr/omaf272
Availability: https://doi.org/10.1093/omcr/omaf272; https://academic.oup.com/omcr/article-pdf/2025/12/omaf272/66128362/omaf272.pdf
Rights: https://creativecommons.org/licenses/by/4.0/
Accession Number: edsbas.3F1607D4
Database: BASE