Spatiotemporal development of late and moderate preterm infant gut and oral microbiomes and impact of gestational age on early colonization
| Title: | Spatiotemporal development of late and moderate preterm infant gut and oral microbiomes and impact of gestational age on early colonization |
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| Authors: | Ahearn-Ford S; Kakaroukas A; Young GR; Nelson A; Abrahamse-Berkeveld M; van Elburg RM; Smith D; Berrington JE; Embleton ND; Stewart CJ |
| Source: | mSystems, 17 December 2025 |
| Publisher Information: | American Society for Microbiology |
| Publication Year: | 2025 |
| Collection: | Newcastle University Library ePrints Service |
| Description: | Microbiome research focusing on late and moderate preterm infants (LMPT; 32 to 36 weeks gestation) is limited, despite rising LMPT births, large healthcare burdens, and increased risks of multiple morbidities, potentially microbially related. In this longitudinal cohort study, 16S rRNA gene sequencing was used to analyze 371 stool and 402 saliva samples from 160 LMPT infants, collected at five time points between birth and 12 months corrected age (CA), to describe spatial and temporal variability in gut and oral microbiomes. Paired stool and saliva samples (n = 337) were analyzed for potential microbial relationships. Early LMPT samples (up to 60 days of life; DOL) were also compared with data from seven extremely preterm infants (EP; |
| Document Type: | article in journal/newspaper |
| File Description: | application/pdf |
| Language: | unknown |
| Relation: | https://eprints.ncl.ac.uk/309594; https://eprints.ncl.ac.uk/fulltext.aspx?url=309594/3E6DD77E-FB73-4D91-93E6-948C29BBA0D9.pdf&pub_id=309594 |
| Availability: | https://eprints.ncl.ac.uk/309594 |
| Rights: | https://creativecommons.org/licenses/by/4.0/ |
| Accession Number: | edsbas.3F4ACFF1 |
| Database: | BASE |