| Title: |
Mandibular Advancement for Obstructive Sleep Apnea: Relating Outcomes to Anatomy |
| Authors: |
Friedman, Michael; Hamilton, Craig S.; Samuelson, Christian G. |
| Source: |
Otolaryngology–Head and Neck Surgery ; volume 147, issue S2 ; ISSN 0194-5998 1097-6817 |
| Publisher Information: |
Wiley |
| Publication Year: |
2012 |
| Collection: |
Wiley Online Library (Open Access Articles via Crossref) |
| Description: |
Objective Previous studies assessing the correlation between airway anatomic factors and success with oral appliance (OA) therapy in the treatment of obstructive sleep apnea (OSA) have failed to reach consensus. We aim to assess the role of regional upper airway obstruction measured by acoustic pharyngometry as a determinant of OA success. Method In this outpatient case‐series, data from OSA patients (100% CPAP‐failures) fitted with a custom OA between 07/2011‐01/2012 were reviewed. Regional maximal upper airway collapse was determined on acoustic pharyngometry and classified as retropalatal (RP), retroglossal (RG), or retroepiglottic (RE). Apnea‐hypopnea index (AHI) improvement on titration‐polysomnography was assessed against regional collapse. Results Seventy‐five patients (74.7% male, age 49.0 ± 13.6, BMI 29.4 ± 5.2, mean AHI 30.6 ± 20.0) were assessed and their data grouped on the basis of region of maximal collapse on pharyngometry at respiratory residual volume (RP = 29, RG = 28, RE = 18). Overall AHI reduction at OA‐titration was –20.2 (95% CI –23.6, –16.8; P 50% AHI reduction plus AHI |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1177/0194599812451438a271 |
| Availability: |
http://dx.doi.org/10.1177/0194599812451438a271; https://onlinelibrary.wiley.com/doi/pdf/10.1177/0194599812451438a271 |
| Rights: |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
| Accession Number: |
edsbas.4015FD8E |
| Database: |
BASE |