| Title: |
0614 Characterizing Sleep in Early-Morning Shift Workers at Risk for Shift Work Disorder |
| Authors: |
Zitting, Kirsi-Marja; Gilmore, Katherine; Elkhadem, Alexandria; Shaw, Samantha; Deminico, Marena; Lockyer, Brandon; Quan, Stuart; Wang, Wei; Issa, Nicolas; Williams, Jonathan; Duffy, Jeanne; Czeisler, Charles |
| Source: |
SLEEP ; volume 46, issue Supplement_1, page A269-A270 ; ISSN 0161-8105 1550-9109 |
| Publisher Information: |
Oxford University Press (OUP) |
| Publication Year: |
2023 |
| Description: |
Introduction Shift work is increasingly common in our 24/7 society and can cause sleep disturbances and excessive sleepiness. Roughly 10-43% of shift workers are diagnosed with shift work disorder (SWD), characterized by excessive sleepiness accompanied by reduced sleep duration and/or insomnia. While more individuals work early morning shifts (shift start 3-6AM) compared to overnight shifts, few studies have investigated this population. The aim of this study was to characterize sleep in a population of early-morning shift workers. Methods We characterized sleep in early-morning shift workers (18-65yrs) from New England who were screened for a clinical trial of a wake-promoting agent. Pre-screening consisted of the Epworth Sleepiness Scale (ESS) and a Shift Work Disorder Questionnaire (SWD); screening consisted of the Pittsburg Sleep Quality Index Questionnaire Questionnaire (PSQI) ; a physical exam including an ECG, CBC, urinalysis, and comprehensive metabolic panel; a home sleep test (HST), a Monitored Wakefulness Test (MWT); a physician evaluation of their excessive sleepiness (Clinical Global Impression [CGI]); and a self-evaluation regarding how sleepiness affected their everyday life (Patient Global Impression [PGI]). Only data from consented individuals who met the initial inclusion criteria of being high risk for SWD were included in the analysis. Results 158 early-morning shift workers met the pre-screening criteria and began the screening process. Most worked in retail, healthcare, maintenance, or transportation, and worked five shifts (65%) and 40+ hours (72%) per week, with a duration of 8.8±1.9 hours. 41 were screened out for abnormal findings on the PE, ECG, or screening blood/urine tests; 26 were screened out for previously un-diagnosed OSA or PLMD; 4 were ineligible for other reasons; 7 were excluded after their MWT due to long sleep latency, 20 were lost to follow-up/withdrew and 60 completed screening and met inclusion criteria. Their average (±sd) age was 37±11 years, 45% women, PSQI ... |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1093/sleep/zsad077.0614 |
| Availability: |
https://doi.org/10.1093/sleep/zsad077.0614; https://academic.oup.com/sleep/article-pdf/46/Supplement_1/A269/50466740/zsad077.0614.pdf |
| Rights: |
https://academic.oup.com/pages/standard-publication-reuse-rights |
| Accession Number: |
edsbas.40CD38F2 |
| Database: |
BASE |