| Title: |
Evolution of Zika prevalence in a dengue hyperendemic municipality in Southern Mexico after the outbreak of 2015 to 2017 |
| Authors: |
Gaspar-Castillo, Carlos; Cortes-Escamilla, Anais; Aparicio-Antonio, Rodrigo; Carnalla, Martha; López, Susana; Sánchez-Tacuba, Liliana; Oceguera-Cabrera, Alfonso; Burrone, Óscar; González-Bonilla, César; Ortiz Navarrete, Vianney; Martínez-Barnetche, Jesus; Rodríguez, Mario Henry; Alpuche-Aranda, Celia M |
| Source: |
Salud Pública de México; Vol. 66 No. 3, may-jun (2024); 218-225 ; Salud Pública de México; Vol. 66 Núm. 3, may-jun (2024); 218-225 ; 1606-7916 ; 0036-3634 |
| Publisher Information: |
Instituto Nacional de Salud Pública |
| Publication Year: |
2024 |
| Collection: |
Salud Pública de México (E-Journal) |
| Subject Terms: |
Zika seroprevalence; dengue-endemic area; surveillance; population-based serosurveys |
| Description: |
Objective. Estimate the Zika prevalence in a dengueendemic municipality in Mexico, after the outbreak of 2015 to 2017. Materials and methods. Three serosurveys were conducted in Tapachula, Chiapas, in September 2018, March 2019 and November 2019. A commercial ZIKV and DENV anti-NS1 IgG ELISA were used to estimate each prevalence, their performance and adjustment of the cut-off value were compared with an in-house DENVs and ZIKV anti-EDIII IgG ELISA and the microneutralization test. Results. The anti-NS1 ZIKV titers decreased over time, causing that Zika prevalence decreased from 78.02 to 45.22%, while anti-NS1 DENV titers increased, and the prevalence remained above 95% over a two-year period. Conclusion. Optimal Zikaprevalence estimates can be obtained in a two-years period after outbreaks in dengue-endemic areas. The extension of the Zika outbreak is significantly higher than previously reported in Tapachula, highlighting the underreport of cases based on the routine flavivirus surveillance system in Mexico. ; Objective. Estimate the Zika prevalence in a dengueendemic municipality in Mexico, after the outbreak of 2015 to 2017. Materials and methods. Three serosurveys were conducted in Tapachula, Chiapas, in September 2018, March 2019 and November 2019. A commercial ZIKV and DENV anti-NS1 IgG ELISA were used to estimate each prevalence, their performance and adjustment of the cut-off value were compared with an in-house DENVs and ZIKV anti-EDIII IgG ELISA and the microneutralization test. Results. The anti-NS1 ZIKV titers decreased over time, causing that Zika prevalence decreased from 78.02 to 45.22%, while anti-NS1 DENV titers increased, and the prevalence remained above 95% over a two-year period. Conclusion. Optimal Zikaprevalence estimates can be obtained in a two-years period after outbreaks in dengue-endemic areas. The extension of the Zika outbreak is significantly higher than previously reported in Tapachula, highlighting the underreport of cases based on the routine flavivirus surveillance system in ... |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
English |
| Relation: |
https://saludpublica.mx/index.php/spm/article/view/15407/12556; https://saludpublica.mx/index.php/spm/article/view/15407 |
| DOI: |
10.21149/15407 |
| Availability: |
https://saludpublica.mx/index.php/spm/article/view/15407; https://doi.org/10.21149/15407 |
| Rights: |
Derechos de autor 2024 Salud Pública de México ; https://creativecommons.org/licenses/by-nc-sa/4.0 |
| Accession Number: |
edsbas.41576DE |
| Database: |
BASE |