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Relationship between LTAS-based spectral moments and acoustic parameters of hypokinetic dysarthria in Parkinson's disease

Title: Relationship between LTAS-based spectral moments and acoustic parameters of hypokinetic dysarthria in Parkinson's disease
Authors: Švihlík J.; Illner V.; Krýže P.; Sousa M.; Krack P.; Tripoliti E.; Jech R.; Rusz J.
Publisher Information: ISCA - International Speech Communication Association
Publication Year: 2023
Collection: Czech Technical University in Prague: Digital Library / České vysoké učení technické v Praze: Digitální knihovna ČVUT
Subject Terms: acoustic parameters; dysarthria; long-term averaged spectrum; Parkinson's disease; spectral moments; speech disorder; STN-DBS
Description: Although long-term averaged spectrum (LTAS) descriptors can detect the change in dysarthria of patients with Parkinson's disease (PD) due to subthalamic nucleus deep brain stimulation (STN-DBS), the relationship between LTAS variables with measures that relate to laryngeal physiology remain unknown. We aimed to find connections between LTAS-based moments and the main acoustic characteristics of hypokinetic dysarthria in PD as the response to STN-DBS stimulation changes. We analyzed reading passages of 23 PD patients in ON and OFF STN-DBS states compared to 23 healthy controls. We found a relation between the stimulation-induced change in several spectral moments and acoustic parameters representing voice quality, articulatory decay, articulation rate, and mean fundamental frequency. While the difference between PD and controls was significant across most acoustic descriptors, only the spectral mean and fundamental frequency variability could differentiate between ON and OFF conditions.
Document Type: conference object
File Description: application/pdf
Language: English
Relation: Proceedings of the Annual Conference of the International Speech Communication Association, INTERSPEECH 2023; info:eu-repo/grantAgreement/Czech Science Foundation/GF/GF21-14216L/CZ/Reducing speech-related side-effects of deep brain stimulation in Parkinson's Disease via automated speech analysis/RESPEECH-PD; info:eu-repo/grantAgreement/Ministry of Education, Youth and Sports/LX/LX22NPO5107/CZ/National institute for Neurological Research/NPO-NEURO-D; Interspeech; http://hdl.handle.net/10467/111957
DOI: 10.21437/Interspeech.2023-1722
Availability: http://hdl.handle.net/10467/111957; https://doi.org/10.21437/Interspeech.2023-1722
Rights: openAccess
Accession Number: edsbas.41984D93
Database: BASE