Schematic representation of relevant cell polarization events during budding yeast mating projection growth.
| Title: | Schematic representation of relevant cell polarization events during budding yeast mating projection growth. |
|---|---|
| Authors: | Samhita P. Banavar (4778580); Michael Trogdon (4778586); Brian Drawert (437505); Tau-Mu Yi (257804); Linda R. Petzold (7435412); Otger Campàs (4778583) |
| Publication Year: | 2021 |
| Collection: | Smithsonian Institution: Digital Repository |
| Subject Terms: | Biophysics; Microbiology; Cell Biology; Genetics; Molecular Biology; Physiology; Evolutionary Biology; Developmental Biology; Cancer; Hematology; Infectious Diseases; Computational Biology; Biological Sciences not elsewhere classified; Physical Sciences not elsewhere classified; Coordinating cell polarization; Cell Wall Integrity pathway; projection tip; cell changes shape; cell shape; cell polarization; coarse-grained continuum description; morphogenesi; mating projection growth; yeast mating projection growth |
| Description: | A , Transmitted light image of a S. cerevisiae cell growing a mating projection in the presence of α -factor. Scale bar, 2 μ m. b-e , Sketch of molecular events leading to the polarization of the cell during the growth of the mating projection. B , Cdc42 polarizes and recruits Bni1. C , Bni1, a formin, nucleates actin filaments. D , Membrane vesicles travel along actin cables bringing in Cdc42. E , The CWI pathway couples the mechanics of the cell wall to Bni1 activation via Rho1. F , Geometrical representation of the system and definition of the relevant variables: s , arc length from the apex, ϕ azimuthal angle, r local cell width, θ angle between the local outward normal () and the axis of growth (z) and h thickness of the cell wall. G , Sketch depicting the increasing cell wall viscosity and decreasing cell wall assembly away from the apex. The inset depicts local normal force balance at the cell wall. All variables are defined in the main text. |
| Document Type: | still image |
| Language: | unknown |
| Relation: | https://figshare.com/articles/figure/Schematic_representation_of_relevant_cell_polarization_events_during_budding_yeast_mating_projection_growth_/13660713 |
| DOI: | 10.1371/journal.pcbi.1007971.g001 |
| Availability: | https://doi.org/10.1371/journal.pcbi.1007971.g001 |
| Rights: | CC BY 4.0 |
| Accession Number: | edsbas.41BCF818 |
| Database: | BASE |