| Title: |
Management of bile acid diarrhea in Italy: a survey |
| Authors: |
Marasco G.; Barbara G.; Bellini M.; Portincasa P.; Stanghellini V.; Annibale B.; Benedetti A.; Cammarota G.; Fries W.; Usai Satta P.; Corazziari E. S. |
| Contributors: |
Marasco, G.; Barbara, G.; Bellini, M.; Portincasa, P.; Stanghellini, V.; Annibale, B.; Benedetti, A.; Cammarota, G.; Fries, W.; Usai Satta, P.; Corazziari, E. S. |
| Publication Year: |
2025 |
| Collection: |
IRIS Università degli Studi di Bologna (CRIS - Current Research Information System) |
| Subject Terms: |
Bile acid diarrhea; Cholestyramine; Colesevelam; Diarrhea; Irritable bowel syndrome; Survey |
| Description: |
Bile acid diarrhea (BAD) is a common, under-investigated cause of chronic diarrhea. We aimed to assess the current management of BAD among a group of Italian physicians. A survey was developed by a task force of experts and distributed via the Internet to Italian physicians members of the main Italian gastroenterological associations. Ninety-four physicians accepted to participate, of whom 44% were females. The majority of participants were gastroenterologists (63%) and the mean age was 50.5years. No differences in the rate of BAD diagnosis among patients with chronic diarrhea were found according to medical specialization. Gastroenterologists reported a higher prevalence of BAD compared with other physicians/general practitioners (1% vs 0.3%). BAD suspicion is mostly raised in the presence of watery stools and > 3 bowel movements/day and the exclusion of organic/drug-related diseases. BAD diagnosis was assessed with 75SeHCAT (67.8% of gastroenterologists and 51.4% of other physicians), followed by a trial of cholestyramine (30.5% of gastroenterologists and 31.4% of other physicians). Therapies most prescribed for BAD were cholestyramine, a low-fat diet, and stool thickeners. BAD is a common condition generally suspected in the presence of chronic watery diarrhea. 75SeHCAT availability influences the awareness of this disease. Therapies currently are often not able to guarantee adequate symptom relief. |
| Document Type: |
article in journal/newspaper |
| File Description: |
ELETTRONICO |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/40938350; info:eu-repo/semantics/altIdentifier/wos/WOS:001571558200001; volume:20; issue:7; firstpage:2079; lastpage:2088; numberofpages:10; journal:INTERNAL AND EMERGENCY MEDICINE; https://hdl.handle.net/11585/1039312 |
| DOI: |
10.1007/s11739-025-04060-9 |
| Availability: |
https://hdl.handle.net/11585/1039312; https://doi.org/10.1007/s11739-025-04060-9; https://link.springer.com/article/10.1007/s11739-025-04060-9 |
| Rights: |
info:eu-repo/semantics/openAccess ; license:Licenza per Accesso Aperto. Creative Commons Attribuzione (CCBY) ; license uri:iris.PUB15 |
| Accession Number: |
edsbas.428AE794 |
| Database: |
BASE |