| Title: |
Associations between fruit and vegetable intakes and incident depression in middle-aged and older adults from 10 diverse international longitudinal cohorts |
| Authors: |
Matison, AP; Flood, VM; Lam, BCP; Lipnicki, DM; Tucker, KL; Preux, PM; Guerchet, M; d'Orsi, E; Quialheiro, A; Rech, CR; Skoog, I; Najar, J; Rydberg Sterner, T; Scarmeas, N; Kosmidis, MH; Yannakoulia, M; Gureje, O; Ojagbemi, A; Bello, T; Shahar, S; Fakhruddin, NNINM; Rivan, NFM; Anstey, KJ; Cherbuin, N; Mortby, ME; Ho, R; Brodaty, H; Sachdev, PS; Reppermund, S; Mather, KA |
| Source: |
urn:ISSN:0165-0327 ; urn:ISSN:1573-2517 ; Journal of Affective Disorders, 359, 373-381 |
| Publisher Information: |
Elsevier |
| Publication Year: |
2024 |
| Collection: |
UNSW Sydney (The University of New South Wales): UNSWorks |
| Subject Terms: |
32 Biomedical and Clinical Sciences; 4206 Public Health; 42 Health Sciences; 3210 Nutrition and Dietetics; Aging; Women's Health; Behavioral and Social Science; Mental Illness; Mental Health; Nutrition; Depression; Brain Disorders; Clinical Research; Prevention; 2.1 Biological and endogenous factors; 2.3 Psychological; social and economic factors; Humans; Vegetables; Female; Male; Fruit; Aged; Middle Aged; Longitudinal Studies; Diet; Incidence; Longitudinal study; Older adults; Cohort Studies of Memory in an International Consortium (COSMIC) |
| Description: |
Background: Emerging observational evidence supports a role for higher fruit and vegetable intake in protecting against the development of depression. However, there is a scarcity of research in older adults or in low- to middle-income countries (LMICs). Methods: Participants were 7801 community-based adults (mean age 68.6 ± 8.0 years, 55.8 % female) without depression, from 10 diverse cohorts, including four cohorts from LMICs. Fruit and vegetable intake was self-reported via comprehensive food frequency questionnaire, short food questionnaire or diet history. Depressive symptoms were assessed using validated measures, and depression defined applying validated cut-offs. The associations between baseline fruit and vegetable intakes and incident depression over a follow-up period of three to nine years were examined using Cox regression. Analyses were performed by cohort with results meta-analysed. Results: There were 1630 cases of incident depression (21 % of participants) over 40,258 person-years of follow-up. Higher intake of fruit was associated with a lower risk of incident depression (HR 0.87, 95%CI [0.77, 0.99], I 2 = 4 %). No association was found between vegetable intake and incident depression (HR 0.93, 95%CI [0.84, 1.04], I 2 = 0 %). Limitations: Diverse measures used across the different cohorts and the modest sample size of our study compared with prior studies may have prevented an association being detected for vegetable intake. Conclusions: Our study supports a role for fruit, but not vegetable intake in protecting against depression. Research investigating different types of fruits and vegetables using standardised measures in larger cohorts of older adults from low- and middle-income countries is warranted. |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
unknown |
| Relation: |
https://hdl.handle.net/1959.4/102711; https://doi.org/10.1016/j.jad.2024.05.096 |
| DOI: |
10.1016/j.jad.2024.05.096 |
| Availability: |
https://hdl.handle.net/1959.4/102711; https://unsworks.unsw.edu.au/bitstreams/869681b7-f8f9-4933-8b51-7e9cfe1d5bcd/download; https://doi.org/10.1016/j.jad.2024.05.096 |
| Rights: |
open access ; https://purl.org/coar/access_right/c_abf2 ; CC-BY ; https://creativecommons.org/licenses/by/4.0/ ; CC BY ; free_to_read |
| Accession Number: |
edsbas.43699F7A |
| Database: |
BASE |