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Incidence of ventricular tachyarrhythmias during permanent pacemaker therapy in low-risk patients results from the German multicentre EVENTS study

Title: Incidence of ventricular tachyarrhythmias during permanent pacemaker therapy in low-risk patients results from the German multicentre EVENTS study
Authors: Faber, Thomas S.; Gradinger, Robert; Treusch, Sven; Morkel, Carsten; Brachmann, Johannes; Bode, Christoph; Zehender, Manfred; for the EVENTS Investigators
Publisher Information: Oxford University Press
Publication Year: 2007
Collection: HighWire Press (Stanford University)
Subject Terms: Arrhythmia/electrophysiology
Description: Aims Current studies found an incidence of 12–31% ventricular tachyarrhythmias and sudden cardiac death during cardiac pacing months or even years after pacemaker insertion. MADIT12 and MUSTT13 demonstrated that patients with poor LV function after Myocardial infarction (MI) showing non-sustained ventricular tachycardia (nsVT) and inducibility during electrophysiologic testing benefit from an ICD. The present study was dedicated to assess the global incidence of non-sustained ventricular arrhythmias in a general population of pacemaker patients. Special regard was on patients with a potential ICD indication, e.g. those matching the MADIT/MUSTT criteria. Methods and results Two hundred and thirty-one patients (72 ± 11 years; 134 men) with an indication for dual chamber pacing entered the study. In all patients pacemaker systems capable of automatic storing of intracardiac electrocardiograms were implanted (Pulsar®, Discovery®, Guidant). Follow-up time was 15 months after inclusion. In 54 (25.7%) of 210 patients with at least one follow-up, episodes of nsVT were documented by stored electrocardiograms (up to >30 beats, >200 b.p.m.). Multiple—up to nine—episodes of ventricular tachycardia were retrieved in 31 of these patients. Three out of 14 patients with an LVEF
Document Type: text
File Description: text/html
Language: English
Relation: http://eurheartj.oxfordjournals.org/cgi/content/short/28/18/2238; http://dx.doi.org/10.1093/eurheartj/ehm242
DOI: 10.1093/eurheartj/ehm242
Availability: http://eurheartj.oxfordjournals.org/cgi/content/short/28/18/2238; https://doi.org/10.1093/eurheartj/ehm242
Rights: Copyright (C) 2007, European Society of Cardiology
Accession Number: edsbas.43CB6C04
Database: BASE