| Title: |
Hundreds of plant F-box proteins in search of function |
| Authors: |
Varshney, Vishal; Potuschak, Thomas; Yan, Shunping; Noir, Sandra; Genschik, Pascal |
| Contributors: |
Institut de Biologie Moléculaire des Plantes (IBMP); Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS); Huazhong Agricultural University Wuhan (HZAU); ANR-19-CE13-0032,RHiD,Un centre de contrôle majeur dans les réponses aux dommages à l'ADN : fonction et régulation associées au module RBR(2019); ANR-20-SFRI-0012,STRAT'US,Façonner les talents en formation et en recherche à l'Université de Strasbourg(2020); ANR-17-EURE-0023,IMCBio,Integrative Molecular and Cellular Biology(2017) |
| Source: |
ISSN: 0022-0957. |
| Publisher Information: |
CCSD; Oxford University Press (OUP) |
| Publication Year: |
2026 |
| Subject Terms: |
F-box proteins; proteostasis; stress; hormone; degron; ubiquitin; [SDV.BV.BOT]Life Sciences [q-bio]/Vegetal Biology/Botanics; [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry; Molecular Biology/Genomics [q-bio.GN]; [SDV.BC.BC]Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC]; [SDV.BDD]Life Sciences [q-bio]/Development Biology |
| Description: |
International audience ; F-box proteins (FBPs), the substrate-recognition subunits of SCF (SKP1-Cullin1-F-box) E3 ubiquitin ligases, are pivotal regulators of protein turnover and play central roles in shaping cellular signaling dynamics. In plants, the repertoire of FBP-encoding genes has undergone remarkable expansion, giving rise to one of the largest and most functionally diverse protein families in the plant kingdom. This diversification underpins an extensive regulatory capacity, enabling FBPs to modulate processes such as hormone perception, developmental patterning, circadian rhythm, and responses to a wide spectrum of biotic and abiotic stresses. Here, we synthesize recent advances that illuminate the molecular mechanisms governing FBP activity, including insights into substrate recognition and their potential applications. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1093/jxb/erag074 |
| Availability: |
https://hal.science/hal-05514258; https://hal.science/hal-05514258v1/document; https://hal.science/hal-05514258v1/file/erag074.pdf; https://doi.org/10.1093/jxb/erag074 |
| Rights: |
https://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.45468181 |
| Database: |
BASE |