Scheme of the mating pathway Yeast cells detect pheromone via a G-protein coupled receptor.
| Title: | Scheme of the mating pathway Yeast cells detect pheromone via a G-protein coupled receptor. |
|---|---|
| Authors: | Sandrine Pinheiro; Mariona Nadal-Ribelles; Carme Solé; Vincent Vincenzetti; Yves Dusserre; Francesc Posas; Serge Pelet |
| Publication Year: | 2025 |
| Collection: | The University of Auckland: Figshare |
| Subject Terms: | Microbiology; Cell Biology; Genetics; Molecular Biology; Immunology; Developmental Biology; Science Policy; Infectious Diseases; Plant Biology; Biological Sciences not elsewhere classified; two haploid cells; saccharomyces cerevisiae < p; core promoter modulate; ste12 binding sites; binding sites; strong dimer; specific timing; largely encoded; large diversity; basal association |
| Description: | The G-protein disassemble and recruits the scaffold Ste5 at the plasma membrane. Then, Ste20 activates the MAP3K Ste11, which phosphorylates the MAP2K Ste7. Ste7 phosphorylates both MAPK Fus3 and Kss1. Fus3 phosphorylates Far1 to arrest the cell cycle in G1. Both Kss1 and Fus3 contribute to the transcriptional response by inhibiting the repression exerted on the TF Ste12 by Dig1 and Dig2. (PDF) |
| Document Type: | article in journal/newspaper |
| Language: | unknown |
| DOI: | 10.1371/journal.pgen.1011710.s001 |
| Availability: | https://doi.org/10.1371/journal.pgen.1011710.s001; https://figshare.com/articles/journal_contribution/Scheme_of_the_mating_pathway_Yeast_cells_detect_pheromone_via_a_G-protein_coupled_receptor_/29332246 |
| Rights: | CC BY 4.0 |
| Accession Number: | edsbas.45A54643 |
| Database: | BASE |