| Title: |
Risk factors for pandemic (H1N1) 2009 virus seroconversion among hospital staff, Singapore |
| Authors: |
Chen, MIC; Lee, VJM; Barr, I; Lin, C; Goh, R; Lee, C; Singh, B; Tan, J; Lim, WY; Cook, AR; Ang, B; Chow, A; Tan, BH; Loh, J; Shaw, R; Chia, KS; Lin, RTP; Leo, YS |
| Publisher Information: |
CENTERS DISEASE CONTROL |
| Publication Year: |
2010 |
| Collection: |
The University of Melbourne: Digital Repository |
| Description: |
We describe incidence and risk factors for pandemic (H1N1) 2009 virus infection in healthcare personnel during the June-September 2009 epidemic in Singapore. Personnel contributed 3 serologic samples during June-October 2009, with seroconversion defined as a ≥4-fold increase in hemagglutination inhibition titers to pandemic (H1N1) 2009. Of 531 participants, 35 showed evidence of seroconversion. Seroconversion rates were highest in nurses (28/290) and lowest in allied health staff (2/116). Significant risk factors on multivariate analysis were being a nurse (adjusted odds ratio [aOR] 4.5, 95% confidence interval [CI] 1.0-19.6) and working in pandemic (H1N1) 2009 isolation wards (aOR 4.5, 95% CI 1.3-15.6). Contact with pandemic (H1N1) 2009-infected colleagues (aOR 2.5, 95% CI 0.9-6.6) and larger household size (aOR 1.2, 95% CI 1.0-1.4) were of borderline significance. Our study suggests that seroconversion was associated with occupational and nonoccupational risk factors. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| ISSN: |
1080-6040 |
| Relation: |
https://hdl.handle.net/11343/269522 |
| Availability: |
https://hdl.handle.net/11343/269522 |
| Rights: |
https://creativecommons.org/licenses/by/4.0 ; CC BY |
| Accession Number: |
edsbas.46DB7C26 |
| Database: |
BASE |