| Title: |
Transcranial magnetic stimulation (TMS) and repetitive TMS in multiple sclerosis |
| Authors: |
Aloizou A.-M.; Pateraki G.; Anargyros K.; Siokas V.; Bakirtzis C.; Liampas I.; Nousia A.; Nasios G.; Sgantzos M.; Peristeri E.; Dardiotis E. |
| Source: |
Reviews in the Neurosciences ; https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102030452&doi=10.1515%2frevneuro-2020-0140&partnerID=40&md5=dddecc2cc9a09aabcee357f903823093 |
| Publication Year: |
2021 |
| Collection: |
University of Thessaly Institutional Repository / Ιδρυματικό Αποθετήριο Πανεπιστημίου Θεσσαλίας |
| Subject Terms: |
4 aminobutyric acid A receptor; biological marker; natalizumab; Article; cerebellum disease; clinical feature; cognitive defect; comparative effectiveness; cortical excitability; disease association; Expanded Disability Status Scale; fatigue; human; kinesiotherapy; major depression; multiple sclerosis; neuropathology; observational study; open study; phase 2 clinical trial (topic); pilot study; quality of life; randomized controlled trial (topic); repetitive transcranial magnetic stimulation; sham procedure; spasticity; transcranial magnetic stimulation; treatment outcome; urinary tract disease; electroencephalography |
| Description: |
Multiple sclerosis (MS) is the most well-known autoimmune disorder of the central nervous system, and constitutes a major cause of disability, especially in young individuals. A wide array of pharmacological treatments is available, but they have often been proven to be ineffective in ameliorating disease symptomatology or slowing disease progress. As such, non-invasive and non-pharmacological techniques have been gaining more ground. Transcranial magnetic stimulation (TMS) utilizes the electric field generated by a magnetic coil to stimulate neurons and has been applied, usually paired with electroencephalography, to study the underlying pathophysiology of MS, and in repetitive trains, in the form of repetitive transcranial magnetic stimulation (rTMS), to induce long-lasting changes in neuronal circuits. In this review, we present the available literature on the application of TMS and rTMS in the context of MS, with an emphasis on its therapeutic potential on various clinical aspects, while also naming the ongoing trials, whose results are anticipated in the future. © 2021 Walter de Gruyter GmbH, Berlin/Boston. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| ISSN: |
03341763 |
| Relation: |
https://hdl.handle.net/11615/70458 |
| DOI: |
10.1515/revneuro-2020-0140 |
| Availability: |
https://hdl.handle.net/11615/70458; https://doi.org/10.1515/revneuro-2020-0140 |
| Accession Number: |
edsbas.479D76EC |
| Database: |
BASE |