| Title: |
YOUNG INVESTIGATORS COMPETITION, HRC 2013 |
| Authors: |
Phan, T.T.; Khan, S.; Dewhurst, M.; Lee, D.; James, S.; de Belder, M.; Linker, N.J.; Thornley, A.; Turley, A.J.; Ahmed, F.Z.; Arumugam, P.; Allen, S.; Daniels, K.; Clarke, B.; Mamas, M.; James, J.; Zaidi, A.M.; Ullah, W.; Hunter, R.; Lovell, M.; Dhinoja, M.; Earley, M.; Sporton, S.; Schilling, R.; Raju, H.; Hedley, P.; Arno, G.; Ware, J.; Jeffery, S.; Cook, S.; Christiansen, M.; Behr, E.R.; Sohal, M.; Chen, Z.; Sammut, E.; Jackson, T.; Child, N.; Wright, M.; O'Neill, M.; Cooklin, M.; Gill, J.; Carr-White, G.; Razavi, R.; Rinaldi, C.A.; Nunn, L.M.; Lopes, L.; Syrris, P.; Plagnol, V.; Firman, E.; Dalageorgou, C.; Domingo, D.; Zorio, E.; Murday, V.; Findlay, I.; Duncan, A.; Fynn, S.; White, A.; Goddard, M.; Robert, L.; Bueser, T.; Langman, C.; Bundgaard, H.; Ferrero-Miliani, L.; Wheeldon, N.; O'Beirne, A.; Suvarna, S.K.; Lowe, M.D.; McKenna, W.J.; Elliott, P.M.; Lambiase, P.D. |
| Publisher Information: |
Oxford University Press |
| Publication Year: |
2013 |
| Collection: |
HighWire Press (Stanford University) |
| Subject Terms: |
ABSTRACTS |
| Description: |
Introduction: ST-Elevation Myocardial Infarction (STEMI) can cause significant deleterious effects to left ventricular (LV) systolic function. With the widespread introduction of PPCI the recovery in those with severely impaired LV function (EF ≤ 30%) in the acute phase is not well established. Furthermore the indication for a primary prevention ICD post STEMI is dependent on which screening guidance, NICE or ESC, is followed. Methods: Retrospective analysis of all STEMIs presenting to a regional cardiothoracic centre over a 7-year period (2005-2012) treated with PPCI to determine in-hospital mortality, LV function at index presentation, at 3-months and the predicted primary prevention ICD implantation rate using NICE (TA095) and ESC guidelines. Predicted implant rates were compared with actual implantation rates. Patients were identified via a validated MINAP database. Results: 3902 patients (70% male) with mean age 65 ± 13 years underwent PPCI. 264 (6.8%) patients died in hospital. Of the survivors, 3238 (83%) patients had echocardiography during their index presentation with an average length of stay of 4.8 ± 8.5 days. Of these patients, LVEF was normal in 1550 (48%), mild/moderately impaired in 1354 (42%) and severely impaired in 332 (10%) of patients. Of these 332 patients 147 were followed up at our centre. 130 patients had an echocardiogram within 3 months post MI, amongst these, 62 (48%) had severe LV impairment (71% anterior STEMIs, 29% posterior/inferior STEMIs). The number of patients fulfilling NICE and ESC criteria for primary prevention ICD therapy were 6 (10%) and 60 (97%), respectively. The actually number of patient receiving an ICD was 12 (19%). Conclusion: Short term survival following a STEMI treated with PPCI was high (93.2%). However, 10% of patients had severe LV impairment at time of hospital discharge. By 3 months half of these patients demonstrated improvement in LV function on optimal medical therapy. The remaining patients were candidates for primary prevention ICD screening. ... |
| Document Type: |
text |
| File Description: |
text/html |
| Language: |
English |
| Relation: |
http://europace.oxfordjournals.org/cgi/content/short/15/suppl_4/iv1; http://dx.doi.org/10.1093/europace/eut313 |
| DOI: |
10.1093/europace/eut313 |
| Availability: |
http://europace.oxfordjournals.org/cgi/content/short/15/suppl_4/iv1; https://doi.org/10.1093/europace/eut313 |
| Rights: |
Copyright (C) 2013, European Heart Rhythm Association of the European Society of Cardiology (ESC) |
| Accession Number: |
edsbas.4858A92D |
| Database: |
BASE |