O-43 RISK FACTORS FOR CANCER DEVELOPMENT IN PATIENTS WITH PRIMARY BILIARY CHOLANGITIS
| Title: | O-43 RISK FACTORS FOR CANCER DEVELOPMENT IN PATIENTS WITH PRIMARY BILIARY CHOLANGITIS |
|---|---|
| Authors: | Michelle Harriz Braga; Guilherme Grossi Lopes Cançado; Paulo Lisboa Bittencourt; Cláudia Alves Couto; Laura Vilar Guedes; André Mourão Costa Lima; Maria Lucia Gomes Ferraz; Cristiane Alves Villela-Nogueira; Jorge Nardelli Mateus; Luciana Costa Faria; Nathalia Mota De Faria Gomes; Maria Gomes Oliveira Elze; Vivian Rotman; Maria Beatriz Oliveira; Simone Muniz Carvalho Fernandes Cunha; Marlone Cunha-Silva; Liliana Sampaio Costa Mendes; Claudia Alexandra Pontes Ivantes; Liana Codes; Valéria Ferreira De Almeida Borges; Fabio Heleno De Lima Pace; Mario Guimarães Pessoa; Izabelle Venturini Signorelli; Gabriela Perdomo Coral; João Galizzi Filho; Aline Lopes Chagas; Debora Raquel Benedita Terrabuio; Eduardo Luiz Rachid Cançado |
| Source: | Annals of Hepatology, Vol 28, Iss , Pp 101050- (2023) |
| Publisher Information: | Elsevier |
| Publication Year: | 2023 |
| Collection: | Directory of Open Access Journals: DOAJ Articles |
| Subject Terms: | Specialties of internal medicine; RC581-951 |
| Description: | Introduction and Objectives: Primary biliary cholangitis (PBC) and autoimmune hepatitis (AIH) and PBC overlap syndrome (AIH/PBC) have been associated with a higher risk of hepatocellular carcinoma (HCC) and extra-hepatic malignancy (EHM). This study aimed to assess potential risk factors associated with cancer development in PBC and AIH/PBC patients. Materials and Methods: The Brazilian Cholestasis Study Group database was reviewed and analyzed. Results: Among the 752 PBC patients enrolled, 64 of them with AIH/PBC, and 87 cancers were identified in 79 patients, including 20 cases of HCC and 67 of EHM. Patients with HCC had a higher prevalence of cirrhosis (95% vs. 32.5%, p= |
| Document Type: | article in journal/newspaper |
| Language: | English |
| ISBN: | 978-1-66526-812-7; 1-66526-812-3 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S1665268123001540; https://doaj.org/toc/1665-2681; https://doaj.org/article/e13f4266a6884d50b4cddab25431c81a |
| DOI: | 10.1016/j.aohep.2023.101050 |
| Availability: | https://doi.org/10.1016/j.aohep.2023.101050; https://doaj.org/article/e13f4266a6884d50b4cddab25431c81a |
| Accession Number: | edsbas.4914BE12 |
| Database: | BASE |