| Title: |
High-performance wireless powering for peripheral nerve neuromodulation systems |
| Authors: |
Tanabe, Y; Ho, JS; Liu, J; Liao, SY; Zhen, Z; Hsu, S; Shuto, C; Zhu, ZY; Ma, A; Vassos, C; Chen, P; Tse, HF; Poon, ASY |
| Publisher Information: |
//www.plosone.org/home.action; United States |
| Publication Year: |
2017 |
| Collection: |
University of Hong Kong: HKU Scholars Hub |
| Description: |
Neuromodulation of peripheral nerves with bioelectronic devices is a promising approach for treating a wide range of disorders. Wireless powering could enable long-term operation of these devices, but achieving high performance for miniaturized and deeply placed devices remains a technological challenge. We report the miniaturized integration of a wireless powering system in soft neuromodulation device (15 mm length, 2.7 mm diameter) and demonstrate high performance (about 10%) during in vivo wireless stimulation of the vagus nerve in a porcine animal model. The increased performance is enabled by the generation of a focused and circularly polarized field that enhances efficiency and provides immunity to polarization misalignment. These performance characteristics establish the clinical potential of wireless powering for emerging therapies based on neuromodulation. ; published_or_final_version |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
PLoS ONE; PLoS One, 2017, v. 12 n. 10, p. e0186698; e0186698; 289539; WOS:000413568900025; 10; https://hub.hku.hk/handle/10722/259392; 12 |
| DOI: |
10.1371/journal.pone.0186698 |
| Availability: |
https://hub.hku.hk/handle/10722/259392; https://doi.org/10.1371/journal.pone.0186698 |
| Rights: |
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. |
| Accession Number: |
edsbas.4B48C8A6 |
| Database: |
BASE |