| Title: |
Outcomes of Impella 5.5/CP use in acute on chronic heart failure: a single center case series |
| Authors: |
Te Gussinklo, W; Azami, T; Romano, G; Eden, M; Schlegel, P; Kremer, J; Arif, R; Karck, M; Meyer, A |
| Source: |
European Heart Journal ; volume 46, issue Supplement_1 ; ISSN 0195-668X 1522-9645 |
| Publisher Information: |
Oxford University Press (OUP) |
| Publication Year: |
2025 |
| Description: |
Introduction The mortality rate in acute decompensated heart failure (ADHF) is high, which is a result of a cascade of events leading to multiorgan failure. The prognosis depends on the timing of restoration of cardiac output. Patients not responding to medical management require mechanical circulatory support (MCS) which can assist left ventricular function and prevent organ damage. A microaxial flow pump (mAFP), a short-term MCS, can be used temporarily for stabilizing and bridging patients. We report outcomes of mAFP use in patients with pre-existing chronic heart failure presenting with ADHF. Purpose In this study, we intend to provide a detailed analysis of outcomes associated with the use of a mAFP in patients with ADHF. By evaluating multiple variables collected during treatment, we seek to highlight the efficacy, safety, and potential complications of this device. Materials and Methods This is a retrospective single center study. All patients with a history of pre-existing chronic heart failure, presented with ADHF and managed with mAFP were included. The demographic details, past history, type of mAFP and surgical data of implantation were recorded. Pre- and post-mAFP hemodynamic variables and post-implant complications were also evaluated and compared using appropriate statistical tests. Results We included 56 patients in this study. All patients were managed with either the Impella 5.5/5.0 (n=52, 89.7%) or CP (n=6, 10.3%). After mAFP implantation, there was a significant reduction in vasoactive inotropic score (p |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1093/eurheartj/ehaf784.1354 |
| Availability: |
https://doi.org/10.1093/eurheartj/ehaf784.1354; https://academic.oup.com/eurheartj/article-pdf/46/Supplement_1/ehaf784.1354/65179243/ehaf784.1354.pdf |
| Rights: |
https://academic.oup.com/pages/standard-publication-reuse-rights |
| Accession Number: |
edsbas.4B6BA0DE |
| Database: |
BASE |