| Title: |
Agreeing Language in Veterinary Endocrinology (ALIVE): Cushing's Syndrome and Hypoadrenocorticism-A Modified Delphi-Method-Based System to Create Consensus Definitions |
| Authors: |
Niessen, Stijn J M; Behrend, Ellen N; Fracassi, Federico; Church, David B; Foster, Sue F; Galac, Sara; Melian, Carlos; Pöppl, Álan G; Ramsey, Ian K; Sieber-Ruckstuhl, Nadja S; On Behalf Of The Esve/Sce Membership; Interne geneeskunde GD; OnGo; CS_Cancer |
| Publication Year: |
2025 |
| Subject Terms: |
Cushing’s; adrenals; consensus; endocrinology; hypoadrenocorticism; terminology; General Veterinary; SDG 3 - Good Health and Well-being |
| Description: |
Progress in clinical practice, research, and teaching needs a common language. Agreement among veterinary endocrinologists on definitions of concepts related to Cushing's syndrome (CS) and hypoadrenocorticism is lacking. After a successful inaugural cycle on diabetes mellitus terminology, project Agreeing Language in Veterinary Endocrinology (ALIVE) held a second cycle, with simplified methodology, and brought together 10 experts of the European Society of Veterinary Endocrinology (ESVE) and the Society of Comparative Endocrinology (SCE). It employed a four-round modified Delphi Method to generate draft definitions and try and achieve consensus. A final round used an endorsement survey of the expert-generated definitions distributed to the ESVE and SCE memberships, seeking a simple majority endorsement. A minimum of 20% membership participation was sought. The 10 experts achieved 100% consensus on the definition of 35 adrenal disease-associated concepts, including disease definitions, diagnostic criteria, and test definitions, a disease classification system for CS and hypoadrenocorticism, and a clinical scoring system for CS. Definitions were subsequently assessed by 78 ESVE and SCE members (26% of combined memberships). All definitions achieved a simple majority, ranging from 83.1 to 100%. ALIVE proved effective in creating a body of terminology for adrenal disease in companion animals, which met the overall approval of a majority of those participating in the endorsement phase. The prospective use of these definitions could help improve comparability and standards for adrenal disease research, education, and clinics. |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
English |
| ISSN: |
2306-7381 |
| Relation: |
https://dspace.library.uu.nl/handle/1874/478374 |
| Availability: |
https://dspace.library.uu.nl/handle/1874/478374 |
| Rights: |
info:eu-repo/semantics/OpenAccess |
| Accession Number: |
edsbas.4B7741A |
| Database: |
BASE |