| Title: |
Effect of normal aging versus hypertension, abnormal body mass index, and diabetes mellitus on white matter hyperintensity volume |
| Authors: |
King, Kevin S; Peshock, Ronald M; Rossetti, Heidi C; McColl, Roderick W; Ayers, Colby R; Hulsey, Keith M; Das, Sandeep R |
| Source: |
Neuroradiology |
| Publisher Information: |
Barrow - St. Joseph's Scholarly Commons |
| Publication Year: |
2014 |
| Subject Terms: |
aging; white matter hyperintensity; Adult; Age Factors; Aged; 80 and over; Aging (pathology; physiology); Body Mass Index; Brain (pathology); Comorbidity; Diabetes Mellitus (pathology); Ethnicity; Female; Humans; Hypertension (pathology); Image Processing; Computer-Assisted; Magnetic Resonance Imaging; Male; Middle Aged; Obesity (complications; pathology); Regression Analysis; Risk Factors; Sex Factors; Socioeconomic Factors |
| Description: |
BACKGROUND AND PURPOSE: The natural history of white matter hyperintensity (WMH) progression resulting from normal aging versus comorbid vascular insults remains unclear. Therefore we investigated age-related differences in WMH volumes among a group with comorbid hypertension, abnormal body mass index, and diabetes mellitus to a normal aging group drawn from the same population lacking any of these comorbidities. METHODS: WMH volumes were acquired using 3T MRI for 2011 Dallas Heart Study participants. The slope of the WMH versus age regression was compared between normal and comorbidity groups |
| Document Type: |
text |
| Language: |
unknown |
| Relation: |
https://scholar.barrowneuro.org/neuroradiology/48; https://doi.org/10.1161/STROKEAHA.113.003602 |
| DOI: |
10.1161/STROKEAHA.113.003602 |
| Availability: |
https://scholar.barrowneuro.org/neuroradiology/48; https://doi.org/10.1161/STROKEAHA.113.003602 |
| Accession Number: |
edsbas.4E17DA71 |
| Database: |
BASE |