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The Accuracy of Cardiac Surface Conduction Velocity Measurements

Title: The Accuracy of Cardiac Surface Conduction Velocity Measurements
Authors: Vigmond, Edward, J; Massé, Stéphane; Roney, Caroline, H; Bayer, Jason, D; Nanthakumar, Kumaraswamy
Contributors: Institut de Mathématiques de Bordeaux (IMB); Université de Bordeaux (UB)-Institut Polytechnique de Bordeaux (Bordeaux INP)-Centre National de la Recherche Scientifique (CNRS); IHU-LIRYC; Université Bordeaux Segalen - Bordeaux 2-Centre Hospitalier Universitaire de Bordeaux (CHU Bordeaux); University Health Network Toronto, ON, Canada; Queen Mary University of London (QMUL); Drs Vigmond and Bayer were supported by the French Government as part of the “Investments of the Future” program managed by the National Research Agency (ANR), grant reference ANR-10-IAHU-04. Dr Bayer was also supported by the European Union’s Horizon 2020 research and innovation program under the ERA-NET co-fund action no. 680969 with the ANR ERA-CVD SICVALVES grant ANR-19-ECVD-0006 . Dr Roney acknowledges support from a UKRI Future Leaders Fellowship (MR/W004720/1). This work was performed using HPC resources from GENCI-IDRIS (grant A0140310517).; ANR-19-ECVD-0006,SICVALVES,Multiscale Modeling of Valvular Heart Diseases - Understanding the Mechanisms of Adverse Remodeling to Improve Precision Medicine(2019); ANR-10-IAHU-0004,LIRYC,L'Institut de Rythmologie et modélisation Cardiaque(2010); European Project: 680969,H2020-HCO-2014-2015,H2020-HCO-2015,ERA-CVD(2015)
Source: ISSN: 2405-500X ; EISSN: 2405-5018.
Publisher Information: CCSD; Elsevier
Publication Year: 2025
Subject Terms: cardiac mapping; computer simulation; conduction system; conduction velocity; infarct; [SDV]Life Sciences [q-bio]; [SPI]Engineering Sciences [physics]
Description: International audience ; BackgroundConduction velocity (CV) is a measure of the health of myocardial tissue. It can be measured by taking differences in local activation times from intracardiac electrodes. Several factors introduce error into the measurement, among which ignoring the 3-dimensional aspect is a major detriment.ObjectivesThe purpose of this study was to determine if, nonetheless, there was a specific region where CV could be accurately measured.MethodsComputer simulations of 3-dimensional ventricles with a realistic His-Purkinje system were performed. Ventricles also included a dense scar or diffuse fibrosis.ResultsA finer spatial sampling produced better agreement with true CV. Using an error limit of 10 cm/s as a threshold, measurements taken within a region
Document Type: article in journal/newspaper
Language: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/39818672; info:eu-repo/grantAgreement//680969/EU/ERA-NET on cardiovascular diseases to implement joint transnational research projects and set up international cooperations/ERA-CVD; MEDRXIV: 2024.01.26.24301849; PUBMED: 39818672
DOI: 10.1016/j.jacep.2024.11.004
Availability: https://hal.science/hal-05465047; https://hal.science/hal-05465047v1/document; https://hal.science/hal-05465047v1/file/cvacc.pdf; https://doi.org/10.1016/j.jacep.2024.11.004
Rights: https://creativecommons.org/licenses/by-nc-nd/4.0/ ; info:eu-repo/semantics/OpenAccess
Accession Number: edsbas.4E371F0C
Database: BASE