Therapeutic Benefit of Upadacitinib in Severe Post-Proctectomy (Class 4) Perianal Crohn’s Disease: A Three-Patient Case Series
| Title: | Therapeutic Benefit of Upadacitinib in Severe Post-Proctectomy (Class 4) Perianal Crohn’s Disease: A Three-Patient Case Series |
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| Authors: | Hanna, Luke Nathan; Quraishi, Baseer; Pelly, Theo; Lung, Phillip; Tozer, Phil; Hart, Ailsa; Wong, Serre-Yu; Powell, Nick |
| Source: | Inflammatory Bowel Diseases ; ISSN 1078-0998 1536-4844 |
| Publisher Information: | Oxford University Press (OUP) |
| Publication Year: | 2025 |
| Description: | This case series describes striking clinical and radiological responses in 3 Crohn’s disease patients with persistent perineal complications following proctectomy treated with upadacitinib. It highlights the potential of advanced therapies for this refractory inflammatory bowel disease phenotype with limited treatment options. |
| Document Type: | article in journal/newspaper |
| Language: | English |
| DOI: | 10.1093/ibd/izaf216 |
| DOI: | 10.1093/ibd/izaf216/64376494/izaf216.pdf |
| Availability: | https://doi.org/10.1093/ibd/izaf216; https://academic.oup.com/ibdjournal/advance-article-pdf/doi/10.1093/ibd/izaf216/64376494/izaf216.pdf |
| Rights: | https://creativecommons.org/licenses/by/4.0/ |
| Accession Number: | edsbas.4EF8048 |
| Database: | BASE |