| Title: |
Upper gastrointestinal diseases in patients for endoscopy in South-Western Uganda |
| Authors: |
Obayo, S; Muzoora, C; Ocama, P; Cooney, MM; Wilson, T; Probert, CS |
| Source: |
African Health Sciences; Vol 15, No 3 (2015); 959-966 ; 1680-6905 |
| Publisher Information: |
Makerere University Medical School (Uganda) |
| Publication Year: |
2015 |
| Collection: |
AJOL - African Journals Online |
| Subject Terms: |
Upper gastrointestinal symptoms; Pathology; Urease test; Helicobacter pylori; Endoscopy; Uganda |
| Description: |
Background: There is a paucity of published data regarding upper gastrointestinal diseases in Ugandans with upper gastrointestinal symptoms referred for endoscopy.Objectives: To study the presenting complaints, pathology and Helicobacter pylori prevalence among patients with upper gastrointestinal symptoms in South-Western Uganda.Methods: Patients presenting with upper gastrointestinal symptoms underwent upper endoscopy and a urease test for Helicobacter Pylori, all suspicious lesions were biopsied for histopathology review as appropriate.Results: The most common presenting complaints were epigastric pain (51.6%), dysphagia (13.6%) and odynophagia (7.1%). The most common endoscopy finding was gastritis (40.2%), followed by normal examination (15.2%), oesophageal cancer (13.6%), gastric ulcer (7.6%) and gastric cancer (7.1%). Patients older than 40 years (n=110) had significant findings including gastritis (50.9%), oesophageal cancer (22.7%) and gastric cancer (11.8%). However in younger patients, with the age range of 18-40 years (n=74), most examinations were normal (92.9%). Of the 176 patients able to undergo Helicobacter pylori testing 75.6% were positive. Helicobacter pylori infection was associated with statistically significant increase in gastritis, oesophageal cancer, gastric ulcer, gastric cancer, and duodenal ulcers (p-values< 0.05).Conclusion: Gastritis, ulcerative disease, and upper gastrointestinal malignancies are common in South-Western Ugandansand are associated with a high prevalence of Helicobacter pylori. Keywords: Upper gastrointestinal symptoms, Pathology, Urease test, Helicobacter pylori, Endoscopy, Uganda. |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
English |
| Relation: |
http://www.ajol.info/index.php/ahs/article/view/121898/111373; http://www.ajol.info/index.php/ahs/article/view/121898 |
| DOI: |
10.4314/ahs.v15i3.33 |
| Availability: |
http://www.ajol.info/index.php/ahs/article/view/121898; https://doi.org/10.4314/ahs.v15i3.33 |
| Rights: |
Copyright for articles published in this journal is retained by the journal. |
| Accession Number: |
edsbas.4F7A614E |
| Database: |
BASE |