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Complications associated with paediatric airway management during the COVID-19 pandemic: an international, multicentre, observational study

Title: Complications associated with paediatric airway management during the COVID-19 pandemic: an international, multicentre, observational study
Authors: Peterson M. B.; Gurnaney H. G.; Disma N.; Matava C.; Jagannathan N.; Stein M. L.; Liu H.; Kovatsis P. G.; von Ungern-Sternberg B. S.; Fiadjoe J. E.; Arnold P.; Schindler E.; Garcia-Marcinkiewicz A.; Peyton J.; Park R.; Sommerfield A.; Sommerfield D.; Griffis H.; Hu P.; Caccioppola A.; Colletti A.; Dato A.; Fernandez A.; Ortiz A.; Sheik A.; Tutuncu A.; Gily B.; Kueppers B.; Taicher B.; Dietrich C.; Gooden C.; Miller C.; Neder Neto C.; Neumann C.; Ulrichs C.; Altun Bingol D.; Barnes D.; Cumino D.; Ozcengiz D.; Pachter D.; Wong D.; Bayliss E.; Ferrari E.; Greenwood E.; Kiss E.; Ng E.; Izzo F.; Russo F.; Chow G.; Martinez-Mezo G.; Petroz G.; Schalte G.; Soares de Sousa G.; Thomas G.; Wong G.; Barros H.; Gill H.; Lewis H.; Manley H.; Pagowska-Klimek I.; Major J.; Zhong J.; Jonckheer K.; Rubin K.; Saracoglu K.; Bernard L.; Burgoyne L.; Sarmiento L.; Vidaurri L.; Zamora L.; Arellano-Pulido M.; Brooks Peterson M.; Clement M.; Fernandez-Jurado M.; Hartley M.; Johansen M.; Lima M.; Malavazzi M.; Matuszczak M.; Molina Torres M.; Nemeth M.; Rodgers McCormick M.; Stein M.; Teen M.; Theroux M.; Vason M.; Hauser N.; Leister N.; Singh N.; Strassberger-Nerschbach N.; Thompson N.; Woodman N.; Cardoso P.; Ingelmo P.; Kendigelen P.; Kovatsis P.; Lane P.; Olomu P.; Reynolds P.; Abujeta Soria R.; Arellano-Pulido R.; Arumainathan R.; Bonfiglio R.; Carlos R.; King R.; McIntyre R.; Sant Anna R.; Abubakra S.; Bhattacharya S.; Black S.; Ferrario S.; Finamore S.; Ghamari S.; Humphreys S.; Neri S.; Shaik S.; Spall S.; Yucetepe S.; Ellimah T.; Engelhardt T.; Trieschmann U.; Quintao V.; Ames W.; Hatipoglu Z.; Ustalar Ozgen Z.
Contributors: Peterson, M; Gurnaney, H; Disma, N; Matava, C; Jagannathan, N; Stein, M; Liu, H; Kovatsis, P; von Ungern-Sternberg, B; Fiadjoe, J; Arnold, P; Schindler, E; Garcia-Marcinkiewicz, A; Peyton, J; Park, R; Sommerfield, A; Sommerfield, D; Griffis, H; Hu, P; Caccioppola, A; Colletti, A; Dato, A; Fernandez, A; Ortiz, A; Sheik, A; Tutuncu, A; Gily, B; Kueppers, B; Taicher, B; Dietrich, C; Gooden, C; Miller, C; Neder Neto, C; Neumann, C; Ulrichs, C; Altun Bingol, D; Barnes, D; Cumino, D; Ozcengiz, D; Pachter, D; Wong, D; Bayliss, E; Ferrari, E; Greenwood, E; Kiss, E; Ng, E; Izzo, F; Russo, F; Chow, G; Martinez-Mezo, G; Petroz, G; Schalte, G; Soares de Sousa, G; Thomas, G; Wong, G; Barros, H; Gill, H; Lewis, H; Manley, H; Pagowska-Klimek, I; Major, J; Zhong, J; Jonckheer, K; Rubin, K; Saracoglu, K; Bernard, L; Burgoyne, L; Sarmiento, L; Vidaurri, L; Zamora, L; Arellano-Pulido, M; Brooks Peterson, M; Clement, M; Fernandez-Jurado, M; Hartley, M; Johansen, M; Lima, M; Malavazzi, M; Matuszczak, M; Molina Torres, M; Nemeth, M; Rodgers McCormick, M; Teen, M; Theroux, M; Vason, M; Hauser, N; Leister, N; Singh, N; Strassberger-Nerschbach, N; Thompson, N; Woodman, N; Cardoso, P; Ingelmo, P; Kendigelen, P
Publisher Information: John Wiley and Sons Inc; GB
Publication Year: 2022
Collection: Università degli Studi di Milano-Bicocca: BOA (Bicocca Open Archive)
Subject Terms: airway; airway adverse event; COVID-19; paediatric; tracheal intubation
Description: Respiratory adverse events in adults with COVID-19 undergoing general anaesthesia can be life-threatening. However, there remains a knowledge gap about respiratory adverse events in children with COVID-19. We created an international observational registry to collect airway management outcomes in children with COVID-19 who were having a general anaesthetic. We hypothesised that children with confirmed or suspected COVID-19 would experience more hypoxaemia and complications than those without. Between 3 April 2020 and 1 November 2020, 78 international centres participated. In phase 1, centres collected outcomes on all children (age ≤ 18 y) having a general anaesthetic for 2 consecutive weeks. In phase 2, centres recorded outcomes for children with test-confirmed or suspected COVID-19 (based on symptoms) having a general anaesthetic. We did not study children whose tracheas were already intubated. The primary outcome was the incidence of hypoxaemia during airway management. Secondary outcomes included: incidence of other complications; and first-pass success rate for tracheal intubation. In total, 7896 children were analysed (7567 COVID-19 negative and 329 confirmed or presumed COVID-19 positive). The incidence of hypoxaemia during airway management was greater in children who were COVID-19 positive (24 out of 329 (7%) vs. 214 out of 7567 (3%); OR 2.70 (95%CI 1.70–4.10)). Children who had symptoms of COVID-19 had a higher incidence of hypoxaemia compared with those who were asymptomatic (9 out of 51 (19%) vs. 14 out of 258 (5%), respectively; OR 3.7 (95%CI 1.5–9.1)). Children with confirmed or presumed COVID-19 have an increased risk of hypoxaemia during airway management in conjunction with general anaesthesia.
Document Type: article in journal/newspaper
File Description: STAMPA
Language: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/35319088; info:eu-repo/semantics/altIdentifier/wos/WOS:000771954800001; volume:77; issue:6; firstpage:649; lastpage:658; numberofpages:10; journal:ANAESTHESIA; https://hdl.handle.net/10281/556766
DOI: 10.1111/anae.15716
Availability: https://hdl.handle.net/10281/556766; https://doi.org/10.1111/anae.15716
Accession Number: edsbas.4FEAC7D6
Database: BASE