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Microfluidic Device for Rapid (15 min)

Title: Microfluidic Device for Rapid (15 min)
Authors: Automated Microarray Hybridization
Contributors: The Pennsylvania State University CiteSeerX Archives
Source: http://www.clinchem.org/content/51/10/1836.full.pdf.
Collection: CiteSeerX
Description: Background: Current hybridization protocols on mi-croarrays are slow and need skilled personnel. Microflu-idics is an emerging science that enables the processing of minute volumes of liquids to perform chemical, biochemical, or enzymatic analyzes. The merging of microfluidics and microarray technologies constitutes an elegant solution that will automate and speed up microarray hybridization. Methods: We developed a microfluidic flow cell con-sisting of a network of chambers and channels molded into a polydimethylsiloxane substrate. The substrate was aligned and reversibly bound to the microarray printed on a standard glass slide to form a functional microfluidic unit. The microfluidic units were placed on an engraved, disc-shaped support fixed on a rotational
Document Type: text
File Description: application/pdf
Language: English
Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.598.1909; http://www.clinchem.org/content/51/10/1836.full.pdf
Availability: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.598.1909; http://www.clinchem.org/content/51/10/1836.full.pdf
Rights: Metadata may be used without restrictions as long as the oai identifier remains attached to it.
Accession Number: edsbas.50DEC572
Database: BASE