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Brief Report: Isogenic Induced Pluripotent Stem Cell Lines From an Adult With Mosaic Down Syndrome Model Accelerated Neuronal Ageing and Neurodegeneration

Title: Brief Report: Isogenic Induced Pluripotent Stem Cell Lines From an Adult With Mosaic Down Syndrome Model Accelerated Neuronal Ageing and Neurodegeneration
Authors: Murray, A; Letourneau, A; Canzonetta, C; Stathaki, E; Gimelli, S; Sloan-Bena, F; Abrehart, R; Goh, P; Lim, S; Baldo, C; Dagna-Bricarelli, F; Hannan, S; Mortensen, M; Ballard, D; Court, DS; Fusaki, N; Hasegawa, M; Smart, TG; Bishop, C; Antonarakis, SE; Groet, J; Nizetic, D
Publication Year: 2016
Collection: Queen Mary University of London: Queen Mary Research Online (QMRO)
Subject Terms: Down syndrome; Neurodegeneration; Neurogenesis; Neuronal differentiation
Description: This work was supported by the project grants from the KayKendall Leukaemia Fund (KKL632), and Fondation JeromeLejeune (2011B/960), by The Wellcome Trust “LonDownS Con-sortium” Strategic Funding Award (098330/Z/12/Z), and theLee Kong Chian School of Medicine, Nanyang TechnologicalUniversity-Singapore start-up funding grant M4230024 toD.N., by the “AnEUploidy Consorium” grant from FrameworkProgramme 6 from the EU Commission to D.N. and S.E.A., aswell as SNF 144082 and ERC 249968 grants to S.E.A. We alsothank Barts and The London Charity and the grant 520/1489:“Development of a National Centre for Bowel Research andSurgical Innovation (NCBRSI)” for purchase of high contentimaging equipment.
Document Type: article in journal/newspaper
File Description: 2077 - 2084
Language: English
Relation: STEM CELLS; http://qmro.qmul.ac.uk/xmlui/handle/123456789/15766
DOI: 10.1002/stem.1968
Availability: http://qmro.qmul.ac.uk/xmlui/handle/123456789/15766; https://doi.org/10.1002/stem.1968
Rights: Creative Commons Attribution License ; 2015. The authors
Accession Number: edsbas.513441B
Database: BASE