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A new strategy for the stereoselective synthesis of 1,2,3-trisubstituted cyclopropanes

Title: A new strategy for the stereoselective synthesis of 1,2,3-trisubstituted cyclopropanes
Authors: Bohm C.; Schinnerl M.; Bubert C.; Zabel M.; Labahn T.; Parisini E.; Reiser O.
Contributors: Bohm C.; Schinnerl M.; Bubert C.; Zabel M.; Labahn T.; Parisini E.; Reiser O.
Publication Year: 2000
Collection: IRIS Università degli Studi di Bologna (CRIS - Current Research Information System)
Subject Terms: Aldol reaction; Amino aldehyde; Donor-acceptor cyclopropane; Felkin-Anh rule; Nucleophilic additions
Description: The stereoselective synthesis of highly functionalized 1,2,3-trisubstituted cyclopropanes 1 and 2, starting from readily available furans 3 or N-protected pyrrole 4, is described. Furthermore, exceptionally high diastereocontrol in agreement with the Felkin-Anh model was observed for the addition of nucleophiles to the title compounds.
Document Type: article in journal/newspaper
File Description: ELETTRONICO
Language: English
Relation: volume:2000; issue:16; firstpage:2955; lastpage:2965; numberofpages:11; journal:EUROPEAN JOURNAL OF ORGANIC CHEMISTRY; https://hdl.handle.net/11585/916190
Availability: https://hdl.handle.net/11585/916190
Accession Number: edsbas.52035A76
Database: BASE