| Title: |
Prevalence and clinical correlates of depression in the acute phase of first episode schizophrenia |
| Authors: |
Roche, Eric; Clarke, Mary; Browne, Stephen; Turner, Niall; McTuige, Orflaith; Kamali, Moaayad; Kinsellla, Anthony; Larkin, Conall; Waddington, John L; O'Callaghan, Eadbhard |
| Source: |
Irish Journal of Psychological Medicine ; volume 27, issue 1, page 15-18 ; ISSN 0790-9667 2051-6967 |
| Publisher Information: |
Cambridge University Press (CUP) |
| Publication Year: |
2010 |
| Description: |
Background : Reported rates of depression in schizophrenia vary considerably. Objective : To measure the prevalence of depression in a first episode sample of people with schizophrenia. Methods : All referrals with a first episode of schizophrenia diagnosed using SCID interviews were assessed pre-discharge and again six months later. We used the Calgary Depression Scale for Schizophrenia (CDSS) and Positive and Negative Syndrome Scale (PANSS) to assess the severity of symptoms. Results : Pre-discharge, 10.4% of the sample met CDSS criteria for depression. According to the PANSS depression (PANSS -D) subscale, 3% of patients were depressed, with a mean score of 7.48 (SD = 2.97). Only 3% of patients pre-discharge were found to be depressed on both the CDSS and the PANSS-D. Six months later 6.5% were depressed according to the CDSS. However none reached depression criteria according to the PANSS-D. The CDSS correlated with PANSS-D both pre-discharge and at follow-up. Feelings of depression and self-deprecation were the most common symptoms at baseline and follow-up. The CDSS was unrelated to negative symptoms at both stages. A lifetime history of alcohol abuse increased the risk for depression. Conclusion : Rates of depression in this sample were low. The CDSS appears to discriminate between depression and negative symptoms. Like the general population, alcohol misuse is a risk factor for depression in first episode schizophrenia. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1017/s0790966700000860 |
| Availability: |
https://doi.org/10.1017/s0790966700000860; https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0790966700000860 |
| Rights: |
https://www.cambridge.org/core/terms |
| Accession Number: |
edsbas.520B7D89 |
| Database: |
BASE |