| Title: |
Harnessing Team Science in Dementia Research: Insights From the Alzheimer’s Disease Research Group in South Carolina |
| Authors: |
Akter, Sayema; Bawa, Eric Mishio; Riccardi, Nicholas; Amoatika, Daniel A; Miller, Margaret C, MS, Ph.D.; Owens, Otis L, MPH, Ph.D., CAPS; Donelle, Lorie, PhD, RN, FCAN; Angela Murphy, E; Fan, Daping; Moss, Melissa; Waugh, Mihyun Lim; Levkoff, Sue E, ScD, MSW, SM; Hucek, Freda Allyson; Neils-Strunjas, Jean, Ph.D, CCC-SLP; Adams, Swann Arp, Ph.D., MS, FACE; Newman-Norlund, Roger; Newman-Norlund, Sarah, Ph.D.; Hardin, James, Ph.D.; Absher, John; Olatosi, Bankole A, Ph.D.; Li, Xiaoming, Ph.D.; Bakos, Lumi, Ph.D.; McCollum, Quentin; Rorden, Chris; Bonilha, Leonardo; Friedman, Daniela B |
| Source: |
Publications |
| Publisher Information: |
Scholar Commons |
| Publication Year: |
2025 |
| Collection: |
University of South Carolina Libraries: Scholar Commons |
| Subject Terms: |
Alzheimer's disease; dementia; neuroimaging; neurology; public health; Nursing |
| Description: |
Alzheimer's disease and related dementias (ADRD) are complex and rapidly growing public health challenges that require integrative, collaborative approaches. To meet this need, the Alzheimer's Disease Research Center (ADRC) of South Carolina, a state-funded partnership across multiple institutions, has embraced a team science model that brings together expertise from four key disciplines: neuroimaging-neurology, health sciences, molecular biology, and engineering. This paper highlights the work at the University of South Carolina (USC) and how each discipline contributes uniquely yet collaboratively within a recurring loop model framework. Extending from USC's Cancer Prevention and Control Program, the framework guides scientific growth through four iterative phases: discovery, development, delivery, and dissemination. From identifying cellular and molecular biomarkers to applying neuroimaging for early diagnosis, utilizing wearable technologies for real-time monitoring, and analyzing statewide data to understand caregiver burden and health inequities, each group contributes to a comprehensive and translational research cycle. By supporting structured mentorship, cross-disciplinary pilot projects, and shared infrastructure, the ADRC initiatives advance research that is both scientifically rigorous and equity-focused. This approach provides a valuable framework for advancing ADRD research and can inform other institutions aiming to tackle similarly complex health issues from discovery through dissemination. |
| Document Type: |
text |
| File Description: |
application/pdf |
| Language: |
English |
| Relation: |
https://scholarcommons.sc.edu/acorn_pub/815; https://scholarcommons.sc.edu/context/acorn_pub/article/1816/viewcontent/akter_et_al_2025_harnessing_team_science_in_dementia_research_insights_from_the_alzheimer_s_disease_research_group_in.pdf |
| DOI: |
10.1177/25424823251385902; |
| Availability: |
https://scholarcommons.sc.edu/acorn_pub/815; https://doi.org/10.1177/25424823251385902;; https://scholarcommons.sc.edu/context/acorn_pub/article/1816/viewcontent/akter_et_al_2025_harnessing_team_science_in_dementia_research_insights_from_the_alzheimer_s_disease_research_group_in.pdf |
| Rights: |
© The Author(s) 2025. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage) . |
| Accession Number: |
edsbas.521945AC |
| Database: |
BASE |