| Title: |
Acute Mesenteric Ischemia during the COVID-19 Pandemic – An Observational Study |
| Authors: |
Nitin Paul Ambrose; S. Gilbert Samuel Jebakumar; Negine Paul; Ajith John George; Ajith Thomas; Betty Simon; Rohin Mittal; Mark Ranjan Jesudason |
| Source: |
Journal of Nature and Science of Medicine, Vol 8, Iss 4, Pp 324-327 (2025) |
| Publisher Information: |
Wolters Kluwer Medknow Publications |
| Publication Year: |
2025 |
| Collection: |
Directory of Open Access Journals: DOAJ Articles |
| Subject Terms: |
acute mesenteric ischemia; covid-19; mesenteric ischemia; Medicine; Public aspects of medicine; RA1-1270 |
| Description: |
Background and Purpose: COVID-19 infection has been associated with arterial and venous thrombosis, including acute mesenteric ischemia (AMI). Information on AMI during the COVID-19 pandemic is very limited; coagulopathy related to the gastrointestinal system manifests as AMI, a severe complication due to its high morbidity and poorer outcomes. This project aimed to study the clinical profile and outcomes of patients with AMI during the COVID-19 pandemic and compare them with a similar group of patients with AMI prepandemic. Methodology: All patients admitted with AMI between March and December 2020 and March and December 2019 were included. Data were collected from electronic hospital records. Results: Twenty-six patients during the pandemic and 15 in the prepandemic era were admitted with AMI, indicating a 73.3% increase in admissions during the pandemic. Baseline characteristics, coagulation parameters, and overall mortality were similar between both the groups. Venous ischemia rates were 53.8% when compared to 40% in the prepandemic era. Prothrombotic rates were 11.5% when compared to 26.6% during the prepandemic era. During the pandemic, bowel resection rates were 93% (14/15), and backout rates were 7% (1/15) when compared to 60% (6/10) and 40% (4/10), respectively, during the prepandemic era. Conclusions: More AMI was seen during the COVID-19 pandemic, with lower rates of preexisting hypercoagulable states. However, rates of nonoperative management and small bowel resection were higher, with fewer backouts. Deranged coagulation was associated with a higher mortality. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
https://journals.lww.com/10.4103/jnsm.jnsm_85_25; https://doaj.org/toc/2589-627X; https://doaj.org/toc/2589-6288; https://doaj.org/article/513b82a9b8c149a4ba9251cbf30736ec |
| DOI: |
10.4103/jnsm.jnsm_85_25 |
| Availability: |
https://doi.org/10.4103/jnsm.jnsm_85_25; https://doaj.org/article/513b82a9b8c149a4ba9251cbf30736ec |
| Accession Number: |
edsbas.52B82EB |
| Database: |
BASE |