| Title: |
Clinical nephrology - miscellaneous |
| Authors: |
Bantis, Christos; Heering, Peter; Kouri, Nicoletta-Maria; Siekierka-Harreis, Magdalena; Stangou, Maria; Schwandt, Christina; Efstratiadis, George; Rump, Lars-Christian; Ivens, Katrin; Haddiya, Intissar; Houssaini Squalli, Tarik; Laouad, Inass; Ramdani, Benyounes; Bayahia, Rabia; Dimas, Grigorios; Tegos, Thomas; Spiroglou, Sofia; Pitsalidis, Christos; Sioulis, Athanasios; Karamouzis, Ioannis; Savopoulos, Christos; Karamouzis, Michael; Orologas, Anastasios; Hatzitolios, Apostolos; Grekas, Dimitrios; Maixnerova, Dita; Jancova, Eva; Rychlik, Ivan; Rysava, Romana; Merta, Miroslav; Reiterova, Jana; Kolsky, Alexandr; Honsova, Eva; Skibova, Jelena; Tesar, Vladimir; Kendi Çelebi, Zeynep; Calayoglu, Reyhan; Keven, Kenan; Kurultak, Ilhan; Mescigil, Pinar; Erbay, Bülent; Karatan, Oktay; Duman, Neval; Ertürk, Sehsuvar; Nergizoglu, Gökhan; Kutlay, Sim; Sengül, Sule; Ates, Kenan; Marino, F.; Martorano, C.; Bellantoni, M.; Tripepi, R.; Zoccali, C.; Ishizuka, Kiyonobu; Harita, Yutaka; Kajiho, Yuko; Tsurumi, Haruko; Asano, Tatsuo; Nishiyama, Kei; Sugawara, Noriko; Chikamoto, Hiroko; Akioka, Yuko; Yamaguchi, Yutaka; Igarashi, Takashi; Hattori, Motoshi; Heering, Peter J.; Sahay, Manisha; Monova, Daniela V.; Monov, Simeon V.; Wang, Yan-yan; Cheng, Hong; Wang, Guo-qin; Dong, Hong-rui; Chen, Yi-pu; Wang, Chang-jiang; Tang, Yan-ling; Buti, Elisa; Dervishi, Egrina; Bergesio, Franco; Ghiandai, Giulia; Mjeshtri, Anduela; Paudice, Nunzia; Caldini, Anna Lucia; Nozzoli, Chiara; Minetti, Enrico Eugenio; Sun, Li; Feng, Jiangmin; Yao, Li; Fan, Qiuling; Ma, Jianfei; Wang, Lining; Kirsanova, Tatiana; Merkusheva, Liudmila; Ruinihina, Nadezda; Kozlovskaya, Natalia; Elenshleger, Galina; Turgutalp, Kenan; Karabulut, Ümit; Özcan, Türkay; Helvaci, Ilter; Kiykim, Ahmet; Kaul, Anupma; Bhadhuaria, Dharmendra; sharma, Raj; Prasad, Narayan; Gupta, Amit; Clajus, Christian; Schmidt, Julius; Haller, Hermann; Kümpers, Philipp; David, Sascha; Sevillano, Angel M.; Molina, Maria; Gutierrez, Eduardo; Morales, Enrique; Gonzalez, Esther; Hernandez, Eduardo; Praga, Manuel; Conde Olasagasti, Jose L.; Vozmediano Poyatos, Carmen; Illescas, Maria L.; Tallon, Serafin; Uson Carrasco, Jose J.; Roca Muñoz, Ana; Rivera Hernandez, Francisco; Ismail, Gener; Jurubita, Roxana; Andronesi, Andreea; Bobeica, Raluca; Zilisteanu, Diana; Rusu, Elena; Achim, Camelia; Huerta, Ana; Caro, Jara; Gutierrez-Solis, Elena; Pasquariello, Antonio; Pasquariello, Giovanna; Innocenti, Maurizio; Grassi, Giulia; Egidi, Maria Francesca; Öztürk, Oguzhan; Yildiz, Abdülmecit; Gül, Cuma Bülent; Dilek, Kamil; Tylicki, Leszek; Jakubowska, Agnieszka; Weber, Ewa; Lizakowski, Slawomir; Swietlik, Dariusz; Rutkowski, Boleslaw; Postorino, Adele; Costa, Stefano; Cristadoro, Simona; Magazzù, Giuseppe; Bellinghieri, Guido; Savica, Vincenzo; Buemi, Michele; Santoro, Domenico; Lu, Yimin; Shen, Pingyan; Li, Xiao; Xu, Yaowen; Pan, Xiaoxia; Wang, Weiming; Chen, Xiaonong; Zhang, Wen; Ren, Hong; Chen, Nan; Mitic, Branka P.; Cvetkovic, Tatjana; Vlahovic, Predrag; Velickovic Radovanovic, Radmila; Stefanovic, Vladisav; Kostic, Svetislav; Djordjevic, Vidojko; Ao, Qiangguo; Ma, Qiang; Cheng, Qingli; Wang, Xiaodan; Liu, Sheng; Zhang, Ruiqin; Ozturk, Savas; Ozmen, Sehmus; Akin, Davut; Danis, Ramazan; Yilmaz, Mehmet; Hajri, Saida; Barbouche, Samia; Okpa, Henry; Oviasu, Efosa; Ojogwu, Louis; Fotouhi, Nikou; Ghaffari, Ali; Hamzavi, Fateme; Nasri, Hamid; Ardalan, Mohammadreza; Stott, Andy; Ullah, Asad; Anijeet, Hameed; Ahmed, Shahed; Kohli, H.S.; Rajachandran, Raja; Rathi, Manish; Jha, Vivekanand; Sakhuja, Vinay; Yenigun, Ezgi; Dede, Fatih; Turgut, Didem; Koc, Eyup; Akoglu, Hadim; Piskinpasa, Serhan; Ozturk, Ramazan; Odabas, Ali; Bajcsi, Dóra; Ábrahám, Gyürgy; Kemény, Éva; Sonkodi, Sándor; Légrády, Péter; Letoha, Annamária; Constantinou, Kypros; Ondrik, Zoltán; Iványi, Béla; Lucisano, Gaetano; Comi, Nicola; Cianfrone, Paola; Summaria, Chiara; Piraina, Valentina; Talarico, Roberta; Camastra, Caterina; Fuiano, Giorgio; Proletov, Ian; Saganova, Elena; Galkina, Olga; Bogdanova, Evdokiia; Zubina, Irina; Sipovskii, Vasilii; Smirnov, Alexei; Bailly, Elodie; Pierre, Dominique; Kerdraon, Rémy; Grezard, Olivier; Gnappi, Elisa; Delsante, Marco; Galetti, Maricla; Maggiore, Umberto; Manenti, Lucio; Hasan, Mahmud Javed; Muqueet, Md. Abdul; Mostafi, Mamun; Chowdhury, Ismail; Haque, Wasim; Khan, Tasmery; Kang, Yeo-Jin; Bae, Eun Jin; Cho, Hyun Seop; Chang, Se-Ho; Park, Dong Jun; Xu, Gang; Lin, Hongli; Hu, Zhao; Yu, Xueqing; Xing, Changying; Mei, Changlin; Zuo, Li; Ni, Zhaohui; Ding, Xiaoqiang; Li, Detian; Zhang, Qianying; Feng, Xiaobei; Lin, Li |
| Publisher Information: |
Oxford University Press |
| Publication Year: |
2013 |
| Collection: |
HighWire Press (Stanford University) |
| Subject Terms: |
Abstracts |
| Description: |
Introduction and Aims: In the last years aldosterone has been identified as an important mediator of renal injury. In the present study we evaluated the influence of the C-344T polymorphism of aldosterone synthase (CYP11B2) gene, associated with serum aldosterone levels and the development of arterial hypertension, on the clinical course of chronic primary glomerulonephritis. Methods: We studied n=283 patients with biopsy proven primary glomerulonephritis (IgA nephropathy: n=143, focal segmental glomerulosclerosis: n=81, membranous glomerulonephritis: n=59) followed up for 7.0 ± 5.7 years. According to the slope of the curve of reciprocal serum creatinine against time (≥ or < -0.1 dl * mg-1 * year-1) group A (slow progressors, n=192) and group B (fast progressors, n=91) were defined. One hundred healthy volunteers were analysed as controls. Aldosterone synthase gene C-344T polymorphism was determined by PCR amplification. Aldosterone serum levels were determined in n=57 of our patients at the time of renal biopsy. The biopsies of 157 patients were analysed by the same pathologist. The degree of glomerular sclerosis, tubulointerstitial fibrosis and vascular hypertrophy was evaluated. Results: The aldosterone synthase genotype correlated to the aldosterone serum levels (CC/CT: 107 ± 70, TT 243 ± 323 pg/ml, p |
| Document Type: |
text |
| File Description: |
text/html |
| Language: |
English |
| Relation: |
http://ndt.oxfordjournals.org/cgi/content/short/28/suppl_1/i392; http://dx.doi.org/10.1093/ndt/gft140 |
| DOI: |
10.1093/ndt/gft140 |
| Availability: |
http://ndt.oxfordjournals.org/cgi/content/short/28/suppl_1/i392; https://doi.org/10.1093/ndt/gft140 |
| Rights: |
Copyright (C) 2013, European Renal Association - European Dialysis and Transplant Association |
| Accession Number: |
edsbas.530C650D |
| Database: |
BASE |