| Title: |
Assessment of Cardiovascular Disease in Autosomal Dominant Polycystic Kidney Disease |
| Authors: |
Gigante A.; Perrotta A. M.; Tinti F.; Assanto E.; Muscaritoli M.; Lai S.; Cianci R. |
| Contributors: |
Gigante, A.; Perrotta, A. M.; Tinti, F.; Assanto, E.; Muscaritoli, M.; Lai, S.; Cianci, R. |
| Publisher Information: |
MDPI; ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND |
| Publication Year: |
2023 |
| Collection: |
Sapienza Università di Roma: CINECA IRIS |
| Subject Terms: |
autosomal dominant polycystic kidney disease; cardiovascular risk; carotid intima–media thickne; flow-mediated dilation; heart rate variability; left ventricular hypertrophy; pulse wave velocity |
| Description: |
Autosomal dominant polycystic kidney disease (ADPKD) is an inherited kidney disease which leads to progressive kidney failure. About 5–10% of patients requiring renal replacement therapy are affected by ADPKD. Cardiovascular diseases are the main causes of morbidity and mortality in these patients with ADPKD; arterial hypertension (AH) is the first symptom with a very early onset. Anyway, some other cardiovascular abnormalities have been reported in ADPKD regardless of the presence of AH. With this background, we conducted a systematic review, collecting all randomized controlled trials (RCTs) and quasi-RCTs found on the main databases; we evaluated the evidence about different imaging techniques to grade the cardiovascular risk in a very early stage of disease. This review aims to describe all cardiovascular assessments in ADPKD patients to improve clinicians’ ability to discover cardiovascular involvement early, allowing appropriate therapies promptly. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/wos/WOS:001014099500001; volume:13; issue:12; firstpage:1; lastpage:15; numberofpages:15; journal:APPLIED SCIENCES; https://hdl.handle.net/11573/1685178 |
| DOI: |
10.3390/app13127175 |
| Availability: |
https://hdl.handle.net/11573/1685178; https://doi.org/10.3390/app13127175 |
| Rights: |
info:eu-repo/semantics/openAccess |
| Accession Number: |
edsbas.5323EF0C |
| Database: |
BASE |