| Title: |
Ly6chi Infiltrating Macrophages Promote Cyst Progression in Injured Conditional Ift88 Mice |
| Authors: |
Aloria, Ernald Jules G.; Song, Cheng J.; Li, Zhang; Croyle, Mandy J.; Mrug, Michal; Zimmerman, Kurt A.; Yoder, Bradley K. |
| Contributors: |
UAB AMC21; PKD Foundation; National Institute of Diabetes and Digestive and Kidney Diseases; Center for Integrated Healthcare, U.S. Department of Veterans Affairs; Detraz Endowed Research Fund in Polycystic Kidney Disease; Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases; NIDDK; Presbyterian Health Foundation; National Institute of General Medical Sciences; National Institutes of Health; UAB Comparative Pathology Laboratory; UAB Heflin Genomic Core |
| Source: |
Kidney360 ; volume 2, issue 6, page 989-995 ; ISSN 2641-7650 |
| Publisher Information: |
Ovid Technologies (Wolters Kluwer Health) |
| Publication Year: |
2021 |
| Description: |
Key Points Ly6c hi infiltrating macrophage numbers are increased in injured, conditional Ift88 mice, compared with controls. Loss of Ly6c hi infiltrating macrophages slows injury-accelerated cystic disease. Ly6c hi infiltrating macrophages drive cystic disease in non- Pkd1 –deficient cystic models. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.34067/kid.0000882021 |
| DOI: |
10.34067/KID.0000882021 |
| Availability: |
https://doi.org/10.34067/kid.0000882021; https://journals.lww.com/10.34067/KID.0000882021 |
| Accession Number: |
edsbas.53D5F6C3 |
| Database: |
BASE |