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Cognitive remediation therapy to enhance cognition and improve recovery in early psychosis:the ECLIPSE research programme including an RCT

Title: Cognitive remediation therapy to enhance cognition and improve recovery in early psychosis:the ECLIPSE research programme including an RCT
Authors: Wykes, Til; Joyce, Eileen; Csipke, Emese; Stringer, Dominic; Pickles, Andrew; McCrone, Paul; Cella, Matteo; Taylor, Rumina; Tinch-Taylor, Rose; Boadu, Janet; Aarons, Gregory; Birchwood, Max; Dopson, Sue; Fowler, David; Greenwood, Kathryn; Johnson, Sonia; Perez, Jesus; Ritunnano, Rosa; Thompson, Andrew; Upthegrove, Rachel; Wilson, Jon; Reeder, Clare
Source: Wykes, T, Joyce, E, Csipke, E, Stringer, D, Pickles, A, McCrone, P, Cella, M, Taylor, R, Tinch-Taylor, R, Boadu, J, Aarons, G, Birchwood, M, Dopson, S, Fowler, D, Greenwood, K, Johnson, S, Perez, J, Ritunnano, R, Thompson, A, Upthegrove, R, Wilson, J & Reeder, C 2024, 'Cognitive remediation therapy to enhance cognition and improve recovery in early psychosis : the ECLIPSE research programme including an RCT', Programme Grants for Applied Research , vol. 12, no. 4. https://doi.org/10.3310/LMFP9667
Publication Year: 2024
Collection: King's College, London: Research Portal
Description: Background: Despite the effectiveness of cognitive remediation, it is not widely implemented because we do not know whether teams will accept it, how much therapist time is needed, whether there are factors which predict lower benefits, whether it is cost-effective and what is required for large-scale roll-out. Objective: To understand the factors that will enhance implementation and benefits of cognitive remediation in Early Intervention Services. Design: Four work packages: (1) focus groups and interviews exploring the development of satisfaction and preference measures for staff and service users; participant team interviews to collect data, before and after introducing cognitive remediation, to understand team dynamics; (2) an observational study of a newly developed therapist e-training programme; (3) a multiarm multistage four-arm randomised controlled trial comparing different amounts of therapist input with Treatment as Usual; and (4) an analysis of trial data to understand potential mediating and moderating factors that affect treatment benefits. Setting: Early Intervention Services in the United Kingdom National Health Service. Participants: Staff and service users in touch with Early Intervention Services. Interventions: For the e-training, we piloted and then provided an e-learning system for training cognitive remediation therapists. For the randomised trial, we provided a cognitive remediation software programme (CIRCuiTS™, King's College London, London) that was delivered in three conditions, all offering up to 42 sessions of cognitive remediation. The conditions were: Intensive (one to one with a therapist), Group treatment with a therapist, Independent with drop-in sessions. Main outcome measures: Work package 1: We developed two satisfaction measures and tested a team dynamic model. Work package 2: Feasibility and acceptability questionnaire, time to complete e-training modules. Work package 3: The personal recovery measure – Goal Attainment Scale. Results: Work package 1: The service user ...
Document Type: article in journal/newspaper
Language: English
DOI: 10.3310/LMFP9667
Availability: https://kclpure.kcl.ac.uk/portal/en/publications/fda8804f-482b-4887-afe9-0501b8bc33eb; https://doi.org/10.3310/LMFP9667; https://www.scopus.com/pages/publications/85199786378
Rights: info:eu-repo/semantics/openAccess
Accession Number: edsbas.540D5E73
Database: BASE