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Melatonin for prevention of delirium in patients receiving mechanical ventilation in the intensive care unit: a multiarm multistage adaptive randomized controlled clinical trial (DEMEL)

Title: Melatonin for prevention of delirium in patients receiving mechanical ventilation in the intensive care unit: a multiarm multistage adaptive randomized controlled clinical trial (DEMEL)
Authors: Mekontso Dessap, Armand; Ricard, Jean-Damien; Contou, Damien; Desnos, Cyrielle; Decavèle, Maxens; Sonneville, Romain; Vivier, Emmanuel; Terzi, Nicolas; Callahan, Jean-Christophe; Jochmans, Sebastien; Leon, Rusel; Carreira, Serge; Nseir, Saad; Chemouni, Frank; Castelain, Vincent; Paul, Muriel; Benoist, Jean-François; Audureau, Etienne; Razazi, Keyvan; de Prost, Nicolas; Carteaux, Guillaume; Gendreau, Segolène; Plantefève, Gaëtan; Pajot, Olivier; Chenal, Amélie; Roux, Damien; Gernez, Coralie; Zucman, Noémie; Fartoukh, Muriel; Labbé, Vincent; Voiriot, Guillaume; Haudebourg, Luc; Faure, Morgane; Demoule, Alexandre; Timsit, Jean-François; Bouadma, Lila; Montmollin, Etienne; Bourdin, Gael; Large, Audrey; Doroszewsky, Fanny; Galerneau, Louis-Marie; Rigault, Guillaume; Candille, Clara; Guitton, Christophe; Landais, Mickaël; Chudeau, Nicolas; le Moal, Mickael; Louistisserand, Maryse; Hraiech, Kmar; Maraffi, Tommaso
Contributors: Programme Hospitalier de Recherche Clinique Inter-Régional 2017; Université Paris-Est Créteil
Source: Intensive Care Medicine ; volume 51, issue 7, page 1292-1305 ; ISSN 0342-4642 1432-1238
Publisher Information: Springer Science and Business Media LLC
Publication Year: 2025
Document Type: article in journal/newspaper
Language: English
DOI: 10.1007/s00134-025-08002-z
DOI: 10.1007/s00134-025-08002-z.pdf
DOI: 10.1007/s00134-025-08002-z/fulltext.html
Availability: https://doi.org/10.1007/s00134-025-08002-z; https://link.springer.com/content/pdf/10.1007/s00134-025-08002-z.pdf; https://link.springer.com/article/10.1007/s00134-025-08002-z/fulltext.html
Rights: https://creativecommons.org/licenses/by-nc/4.0 ; https://creativecommons.org/licenses/by-nc/4.0
Accession Number: edsbas.54471D62
Database: BASE