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Excess direct hospital cost of treating adult patients with ventilator associated respiratory infection (VARI) in Vietnam

Title: Excess direct hospital cost of treating adult patients with ventilator associated respiratory infection (VARI) in Vietnam
Authors: Dat, VQ; Huong, VTL; Turner, HC; Thwaites, L; Van Doorn, HR; Nadjm, B
Publisher Information: Public Library of Science (PLoS)
Publication Year: 2018
Collection: Imperial College London: Spiral
Subject Terms: Adult; Anti-Bacterial Agents; Antimicrobial Stewardship; Cross Infection; Hospital Costs; Humans; Length of Stay; Respiration; Artificial; Vietnam; General Science & Technology
Subject Geographic: United States
Description: INTRODUCTION: Ventilator associated respiratory infections (VARIs) are the most common hospital acquired infections in critical care worldwide. This work aims to estimate the total annual direct hospital cost of treating VARI throughout Vietnam. METHODS: A costing model was constructed to evaluate the excess cost of diagnostics and treatment of VARI in Vietnam. Model inputs included costs for extra lengths of stay, diagnostics, VARI incidence, utilisation of ventilators and antibiotic therapy. RESULTS: With the current VARI incidence rate of 21.7 episodes per 1000 ventilation-days, we estimated 34,428 VARI episodes in the 577 critical care units in Vietnam per year. The extra cost per VARI episode was $1,174.90 and the total annual excess cost was US$40.4 million. A 1% absolute reduction in VARI incidence density would save US$1.86 million annually. For each episode of VARI, the share of excess cost components was 45.1% for critical care unit stay and ventilation, 3.7% for diagnostics and 51.1% for extra antimicrobial treatment. CONCLUSIONS: At the current annual government health expenditure of US$117 per capita, VARI represents a substantial cost to the health service in Vietnam. Enhanced infection prevention and control and antimicrobial stewardship programmes should be implemented to reduce this.
Document Type: article in journal/newspaper
Language: English
Relation: PLoS One; http://hdl.handle.net/10044/1/76126
DOI: 10.1371/journal.pone.0206760
Availability: http://hdl.handle.net/10044/1/76126; https://doi.org/10.1371/journal.pone.0206760
Rights: © 2018 Dat et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited (https://creativecommons.org/licenses/by/4.0/).
Accession Number: edsbas.544C683A
Database: BASE