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Anxiety disorders and stressful events in Takotsubo syndrome

Title: Anxiety disorders and stressful events in Takotsubo syndrome
Authors: Davide Lazzeroni; Matteo Bini; Castiglioni P; Luca Moderato; Chiara Ciracì; Umberto Camaiora; Pietro Tito Ugolotti; Lorenzo Brambilla; Valerio Brambilla; Silvia Garibaldi; Letizia Paglialonga; Valentina Ziveri; Fabrizio Ugo; Nicola Gaibazzi; Paolo Coruzzi
Contributors: Davide, Lazzeroni; Matteo, Bini; Castiglioni, P; Luca, Moderato; Chiara, Ciracì; Umberto, Camaiora; Pietro Tito, Ugolotti; Lorenzo, Brambilla; Valerio, Brambilla; Silvia, Garibaldi; Letizia, Paglialonga; Valentina, Ziveri; Fabrizio, Ugo; Nicola, Gaibazzi; Paolo, Coruzzi
Publication Year: 2017
Collection: IRInSubria - Institutional Repository Insubria (Università degli Studi dell’Insubria)
Description: Background: Anxiety disorders are more common in Takotsubo syndrome (TS) than in acute coronary syndrome patients. Theaim of this study was to investigate whether pre-existing anxiety disorders predispose to TS triggered by exclusively emotional stressful events. Methods: Triggering events were compared in 58 TS patients with and without pre-existing anxiety disorders; clinical, electrocardiographic and echocardiographic data were also collected. Results: Thirty-one (53%) patients had a previous history of anxiety disorders. The exclusively emotional stressful event-rate was higher in TS patients with pre-existing anxiety disorder (74% vs. 30%, p = 0.001), while TS caused by an undetermined trigger were significantly higher in patients without anxiety disorders (33% vs. 10%, p = 0.027). Moreover, in TS patients without a previous history of anxiety disorders, a trend of higher prevalence of physical events was found (16% vs. 37%, p = 0.07). Conclusions: In patients with pre-existing anxiety disorders, TS was predominantly triggered by exclusively emotional stressful events, thereby suggesting a possible relationship between anxiety and emotional cardiac frailty in TS patients.
Document Type: article in journal/newspaper
File Description: ELETTRONICO
Language: unknown
Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:000444545500008; journal:CARDIOLOGY JOURNAL; https://hdl.handle.net/11383/2145164; https://journals.viamedica.pl/cardiology_journal/article/view/54206
DOI: 10.5603/CJ.a2017.0136
Availability: https://hdl.handle.net/11383/2145164; https://doi.org/10.5603/CJ.a2017.0136; https://journals.viamedica.pl/cardiology_journal/article/view/54206
Accession Number: edsbas.545C0A37
Database: BASE