| Title: |
Artemisinin combination therapy mass drug administration in a setting of low malaria endemicity: programmatic coverage and adherence during an observational study in Zanzibar ; Malar J |
| Contributors: |
Ali, Abdullah S.; Thawer, Narjis G.; Khatib, Bakar; Amier, Haji H.; Shija, Joseph; Msellem, Mwinyi; Al-mafazy, Abdul-wahid; Garimo, Issa A.; Mkali, Humphrey; Ramsan, Mahdi M.; Kafuko, Jessica M.; Paxton, Lynn A.; Reithinger, Richard; Ngondi, Jeremiah M. |
| Source: |
Malar J. 16. |
| Collection: |
CDC Stacks (Centers for Disease Control and Prevention) |
| Subject Terms: |
Research; Mass drug administration; Zanzibar; Artemisinin-based combination therapy; Hotspots; Adherence |
| Description: |
Background ; Mass drug administration (MDA) appears to be effective in reducing the risk of malaria parasitaemia. This study reports on programmatic coverage and compliance of MDA using artemisinin-based combination therapy (ACT) in four shehias (smallest administration unit) that had been identified as hotspots through Zanzibar’s malaria case notification surveillance system. ; Methods ; Mass drug administration was done in four shehias selected on the basis of: being an established malaria hot spot; having had mass screening and treatment (MSaT) 2–6 weeks previously; and exceeding the epidemic alert threshold of 5 cases within a week even after MSaT. Communities were sensitized and MDA was conducted using a house-to-house approach. All household members, except pregnant women and children aged less than 2 months, were provided with ACT medicine. Two weeks after the MDA campaign, a survey was undertaken to investigate completion of ACT doses. ; Results ; A total of 8816 [97.1% of eligible; 95% confidence interval (CI) 96.8–97.5] people received ACT. During post MDA surveys, 2009 people were interviewed: 90.2% reported having completed MDA doses; 1.9% started treatment but did not complete dosage; 4.7% did not take treatment; 2.0% were absent during MDA and 1.2% were ineligible (i.e. infants |
| Document Type: |
other/unknown material |
| Language: |
unknown |
| Relation: |
cdc:47690; http://stacks.cdc.gov/view/cdc/47690/ |
| Availability: |
http://stacks.cdc.gov/view/cdc/47690/ |
| Accession Number: |
edsbas.5470B3F4 |
| Database: |
BASE |