| Title: |
Clinical significance of myocardial work parameters after acute myocardial infarction |
| Authors: |
Coisne, Augustin; Fourdinier, Victor; Lemesle, Gilles; Delsart, Pascal; Aghezzaf, Samy; Lamblin, Nicolas; Schurtz, Guillaume; Verdier, Basile; Ninni, Sandro; Delobelle, Antoine; Favata, Francesco; Garret, Camille; Seunes, Claire; Coppin, Amandine; Donal, Erwan; Scotti, Andrea; Latib, Azeem; Granada, Juan; Bauters, Christophe; Montaigne, David |
| Contributors: |
Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires - U 1011 (RNMCD); Institut Pasteur de Lille; Pasteur Network (Réseau International des Instituts Pasteur)-Pasteur Network (Réseau International des Instituts Pasteur)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille); Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille); Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 (RID-AGE); Centre Hospitalier Universitaire de Rennes CHU Rennes = Rennes University Hospital Pontchaillou; Laboratoire Traitement du Signal et de l'Image (LTSI); Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM); Institut Européen de Génomique du Diabète - European Genomic Institute for Diabetes - FR 3508 (EGID); Pasteur Network (Réseau International des Instituts Pasteur)-Pasteur Network (Réseau International des Instituts Pasteur)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre National de la Recherche Scientifique (CNRS); Fédération Française de Cardiologie |
| Source: |
ISSN: 2752-4191 ; European Heart Journal Open ; https://univ-rennes.hal.science/hal-03776182 ; European Heart Journal Open, 2022, 2 (3), pp.oeac037. ⟨10.1093/ehjopen/oeac037⟩. |
| Publisher Information: |
HAL CCSD; Oxford University Press on behalf of the European Society of Cardiology |
| Publication Year: |
2022 |
| Collection: |
Université de Rennes 1: Publications scientifiques (HAL) |
| Subject Terms: |
Myocardial work; Global work efficiency; Myocardial infarction; [SDV.IB]Life Sciences [q-bio]/Bioengineering |
| Description: |
International audience ; Aims To investigate the additional prognostic value of myocardial work (MW) parameters following acute myocardial infarction (AMI). Methods and results Between 2018 and 2020, 244 patients admitted in the cardiac intensive care unit in Lille University Hospital for AMI were included. One-month following AMI, comprehensive transthoracic echocardiography (TTE) was performed to assess parameters of myocardial function. Patients were then followed for major events (ME): cardiovascular death, heart failure, and unplanned coronary revascularization. At 1-month, half of the population was symptomatic (NYHA ≥ II), and medical therapy was almost optimized (angiotensin-converting enzyme inhibitor/angiotensin 2 receptor blocker in 95.5%, beta-blockers in 96.3%, DAPT in 94.7%, and statins in 97.1%). After a median follow-up of 681 (interquartile range: 538–840) days, ME occurred in 26 patients (10.7%). Patients presenting ME were older (65.5 ± 14.2 vs. 58.1 ± 12.1years, P = 0.005) with a higher prevalence of hypertension (65.4 vs. 36.2%, P = 0.004), more impaired left ventricular (LV) function as assessed by LV ejection fraction (P = 0.07), global longitudinal strain (P = 0.03), or MW parameters [P = 0.01 for global work efficiency (GWE)], and greater LV and left atrium dilatations (P = 0.06 for left ventricular end-diastolic volume index and P = 0.03 for left atrial volume index). After adjustment, GWE was the only TTE parameter independently associated with long-term occurrence of ME (P = 0.02). A GWE value |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/35919347; PUBMED: 35919347 |
| DOI: |
10.1093/ehjopen/oeac037 |
| Availability: |
https://univ-rennes.hal.science/hal-03776182; https://univ-rennes.hal.science/hal-03776182v2/document; https://univ-rennes.hal.science/hal-03776182v2/file/oeac037.pdf; https://doi.org/10.1093/ehjopen/oeac037 |
| Rights: |
info:eu-repo/semantics/OpenAccess |
| Accession Number: |
edsbas.547DBD7 |
| Database: |
BASE |