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Comparative evaluation of flat-panel volume CT protocols for high-resolution visualization of middle ear anatomy in human skull specimens

Title: Comparative evaluation of flat-panel volume CT protocols for high-resolution visualization of middle ear anatomy in human skull specimens
Authors: Müller-Graff, Franz-Tassilo; von Düring, Jan; Spahn, Bjoern; Weick, Stefan; Richter, Anne; Grunz, Jan-Peter; Neun, Tilmann; Hackenberg, Stephan; Rak, Kristen
Publication Year: 2026
Collection: Würzburg University: Online Publication Service
Subject Terms: ddc:610
Description: This study evaluates the imaging quality and radiation dose of six flat-panel volume CT protocols with varying technical parameters, including examination time (“Artis Icono” angiography system (Siemens Healthcare AG, Erlangen, Germany): 14s DCT HEAD MICRO CARE (14s I), 14s DCT HEAD MICRO CARE 4 (14s II), 8s DCT HEAD 70kV CARE 1 (8s I), 8s DCT HEAD 70kV CARE 3 (8s II), 4s DCT HEAD CARE FB (4s I), 4s DCT HEAD CARE FB 2 (4s II)) for middle ear visualization in human skull specimens. A scoring system assessed the delineation of 28 anatomical structures, narrowed to eight for detailed evaluation. Protocols 14s I and 8s I achieved the highest image quality, exceeding the clinical threshold. 8s I protocol demonstrated an optimal balance between image quality and radiation safety, adhering to the ALADA principle (“as low as diagnostically acceptable”). While 14s I offered superior detail, it involved higher radiation exposure without substantial further image improvement, indicating a saturation effect. Shorter protocols, such as 4s I, offered radiation-sparing advantages but did not consistently meet clinical image quality standards. Protocol 8s I is recommended as the standard for middle ear imaging, with 4s I as a potential alternative for cases requiring minimized radiation exposure and reduced motion artifact susceptibility.
Document Type: article in journal/newspaper
File Description: application/pdf
Language: English
DOI: 10.1038/s41598-025-33592-5
Availability: https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/43417; https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-434170; https://doi.org/10.1038/s41598-025-33592-5; https://opus.bibliothek.uni-wuerzburg.de/files/43417/41598_2026_Article_33592.pdf
Rights: https://creativecommons.org/licenses/by/4.0/deed.de ; info:eu-repo/semantics/openAccess
Accession Number: edsbas.549EE4D0
Database: BASE