| Title: |
P1363ON-LINE SURVEILLANCE OF ESTABLISHED HAEMODIALYSIS ARTERIOVENOUS FISTULA UTILISING FRESENIUS THERAPY MONITORING SYSTEM AND EUROPEAN CLINICAL DATA SYSTEM (EUCLID): THE SHUNT STUDY- BASELINE DEMOGRAPHICS OF PARTICIPANTS |
| Authors: |
Bodington, Richard; Hazara, Adil; Bhandari, Sunil |
| Source: |
Nephrology Dialysis Transplantation ; volume 35, issue Supplement_3 ; ISSN 0931-0509 1460-2385 |
| Publisher Information: |
Oxford University Press (OUP) |
| Publication Year: |
2020 |
| Description: |
Background and Aims The arteriovenous fistula (AVF) is well established as the preferred vascular access for haemodialysis (HD). However AVF remain prone to a number of complications, the most common of these being thrombosis, which usually occurs on the background of a developing stenosis. The development of stenosis can be detected and the lesion treated before thrombosis occurs; this forms the rationale behind monitoring and surveillance programs. Surveillance uses more resources than monitoring and has not been convincingly shown to improve outcomes such as access loss. The evidence supporting the use of the various monitoring techniques in AVF is in the main observational, under-powered, out of date and based on studies populations of predominantly arteriovenous grafts (AVG). Monitoring techniques have been shown in multiple studies to have higher utility in AVF than AVG. The modern, high efficiency dialysis machine with integrated on-line clearance monitoring (OCM) necessitates the reconsideration of the performance and utility of monitoring metrics such as Kt/V and access recirculation (AR). The lack of evidence surrounding monitoring techniques is recognised by KDOQI who recommend that further research is required to validate these indicators. In this study we aim to examine if changes in AR and Kt/V values obtained through OCM during HD can help predict AVF failure. Method SHUNT is a UK single-centre prospective cohort study with a 1-year follow-up of all study participants. The 100 participants are aged over 18 years receiving in-centre maintenance HD with through an established AVF. We use the Fresenius Therapy Data Monitoring System (F-TDMS) and EuCliD system to capture all dialysis treatment data from Fresenius 5008 machines. This will allow trend analysis for AR and Kt/V to assess the accuracy of these parameters in predicting access failure. The primary outcome measure is to determine whether changes in AR and Kt/V trends are able to predict AVF failure. Secondary outcome measures include ... |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1093/ndt/gfaa142.p1363 |
| Availability: |
https://doi.org/10.1093/ndt/gfaa142.p1363; http://academic.oup.com/ndt/article-pdf/35/Supplement_3/gfaa142.P1363/33357686/gfaa142.p1363.pdf |
| Rights: |
https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model |
| Accession Number: |
edsbas.5553FB83 |
| Database: |
BASE |