| Title: |
Lopinavir/Ritonavir Monotherapy as a Nucleoside Analogue-Sparing Strategy to Prevent HIV-1 Mother-to-Child Transmission: The ANRS 135 PRIMEVA Phase 2/3 Randomized Trial |
| Authors: |
Tubiana, Roland; Mandelbrot, Laurent; Le Chenadec, Jérome; Delmas, Sandrine; Rouzioux, Christine; Hirt, Deborah; Treluyer, Jean-Marc; Ekoukou, Dieudonné; Bui, Eda; Chaix, Marie-Laure; Blanche, Stéphane; Warszawski, Josiane; for the ANRS 135 PRIMEVA (Protease Inhibitor Monotherapy Evaluation) Study Group; Ngondi, J; Chernai, N; Teglas, JP; Laurent, C; Huyn, P; Le Chenadec, J; Delmas, S; Warszawski, J; Muret, P; Baazia, Y; Jeantils, V; Lachassine, E; Rodrigues, A; Sackho, A; Sagnet-Pham, I; Tassi, S; Breilh, D; Iriard, X; Andre, G; Douard, D; Reigadas, S; Roux, D; Louis, I; Morlat, P; Pedebosq, S; Barre, J; Estrangin, E; Fauveau, E; Garrait, V; Ledudal, P; Pichon, C; Richier, L; Thebault, A; Touboul, C; Bornarel, D; Chambrin, V; Clech, L; Dubreuil, P; Foix L'helias, L; Picone, O; Schoen, H; Stralka, M; Crenn-Hebert, C; Floch-Tudal, C; Hery, E; Ichou, H; Mandelbrot, L; Meier, F; Tournier, V; Walter, S; Chevojon, P; Devidas, A; Granier, M; Khanfar-boudjemai, M; Malbrunot, C; Nguyen, R; Ollivier, B; Radideau, E; Turpault, I; Jault, T; Barrail, A; Colmant, C; Fourcade, C; Goujard, C; Pallier, C; Peretti, D; Taburet, AM; Bocket, L; D'angelo, S; Godart, F; Hammou, Y; Houdret, N; Mazingue, F; Thielemans, B; Brochier, C; Cotte, L; Januel, F; Le Thi, T; Gagneux, MC; Bozio, A; Massardier, J; Kebaïli, K; Ben, Akli K; Heller-Roussin, B; Riehl, C; Roos, S; Taccot, F; Winter, C; Arias, J; Brunet-François, C; Dailly, E; Flet, L; Gournay, V; Mechinaud, F; Reliquet, V; Winner, N; Peytavin, G; Bardin, C; Boudjoudi, N; Compagnucci, A; Guerin, C; Krivine, A; Pannier, E; Salmon, D; Treluyer, JM; Firtion, G; Ayral, D; Ciraru-Vigneron, N; Mazeron, MC; Rizzo Badoin, N; Trout, H; Benachi, A; Boissand, C; Bonnet, D; Boucly, S; Blanche, S; Chaix, ML; Duvivier, C; Parat, S; Cayol, V; Oucherif, S; Rouzioux, C; Viard, JP; Bonmarchand, M; De Montgolfier, I; Dommergues, M; Fievet, MH; Iguertsira, M; Pauchard, M; Quetin, F; Soulie, C; Tubiana, R; Faye, A; Magnier, S; Bui, E; Carbonne, B; Daguenel Nguyen, A; Harchi, N; Meyohas, MC; Poirier, JM; Rodriguez, J; Hervé, F; Pialloux, G; Dehee, A; Dollfus, C; Tillous Borde, I; Vaudre, G; Wallet, A; Allemon, MC; Bolot, P; Boussairi, A; Chaplain, C; Ekoukou, D; Ghibaudo, N; Kana, JM; Khuong, MA; Weil, M; Entz-Werle, N; Livolsi Lutz, P; Beretz, L; Cheneau, M; Partisani, ML; Schmitt, MP; Acar, P; Armand, E; Berrebi, A; Guibaud Plo, C; Lavit, M; Nicot, F; Tricoire, J; Ajana, F; Huleux, T |
| Publisher Information: |
Oxford University Press |
| Publication Year: |
2013 |
| Collection: |
HighWire Press (Stanford University) |
| Subject Terms: |
HIV/AIDS |
| Description: |
Background. Prevention of mother-to-child transmission (PMTCT) of human immunodeficiency virus (HIV) is usually based on zidovudine-containing regimens, despite potential toxicities. This multicenter trial evaluated whether lopinavir/ritonavir (LPV/r) monotherapy in HIV type 1–infected women not requiring antiretrovirals for themselves could control maternal viral load (VL). Methods. Overall, 105 pregnant women with baseline VL |
| Document Type: |
text |
| File Description: |
text/html |
| Language: |
English |
| Relation: |
http://cid.oxfordjournals.org/cgi/content/short/57/6/891; http://dx.doi.org/10.1093/cid/cit390 |
| DOI: |
10.1093/cid/cit390 |
| Availability: |
http://cid.oxfordjournals.org/cgi/content/short/57/6/891; https://doi.org/10.1093/cid/cit390 |
| Rights: |
Copyright (C) 2013, Infectious Diseases Society of America |
| Accession Number: |
edsbas.5771FDAE |
| Database: |
BASE |