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Hypertrophic cardiomyopathy with anteriorly directed mitral regurgitation is a red flag for concomitant pathology: A case report

Title: Hypertrophic cardiomyopathy with anteriorly directed mitral regurgitation is a red flag for concomitant pathology: A case report
Authors: Somma, V; Raman, J; Fitzpatrick, L; Prior, D; Paratz, E
Contributors: Sepulveda, EFC; Jakstaite, AM; Cvijic, M; Abdullah, A
Publisher Information: OXFORD UNIV PRESS
Publication Year: 2024
Collection: The University of Melbourne: Digital Repository
Description: BACKGROUND: Hypertrophic cardiomyopathy (HCM) is often linked to systolic anterior motion (SAM) of the mitral valve, typically resulting in a posteriorly directed mitral regurgitation (MR) jet. An anteriorly directed MR jet suggests additional mitral valve pathology that may not be resolved by myectomy alone. CASE SUMMARY: A 58-year-old construction worker with no significant medical history experienced a syncopal event and was admitted to the emergency department with acute pulmonary oedema. A systolic murmur was investigated with a trans-thoracic echocardiogram that revealed severe MR with an unusual anteriorly directed MR jet and a possible flail segment of the posterior leaflet. This finding was further characterized with a trans-oesophageal echocardiogram that revealed severe asymmetric septal hypertrophy with SAM of the mitral valve, severe mitral regurgitation into a dilated left atrium with pulmonary vein flow reversal not caused by HCM-associated SAM, and a markedly abnormal mitral valve with flail and prolapse. The patient underwent successful cardiac surgery, including mitral valve repair and septal myectomy. The patient's recovery was uneventful, allowing for a return to work within a month post-surgery. DISCUSSION: The anteriorly directed MR jet served as a red flag, leading to the discovery of an independent mitral valve pathology that required surgical intervention beyond the expected treatment for SAM-associated HCM. This case highlights the complexity of assessing MR in patients with HCM and underscores the importance of characterizing MR jet direction in diagnosing additional mitral valve diseases.
Document Type: article in journal/newspaper
Language: English
ISSN: 2514-2119
Relation: pii: ytae121; Somma, V., Raman, J., Fitzpatrick, L., Prior, D. & Paratz, E. (2024). Hypertrophic cardiomyopathy with anteriorly directed mitral regurgitation is a red flag for concomitant pathology: A case report. European Heart Journal Case Reports, 8 (3), https://doi.org/10.1093/ehjcr/ytae121.; https://hdl.handle.net/11343/353230
Availability: https://hdl.handle.net/11343/353230
Rights: https://creativecommons.org/licenses/by/4.0 ; CC BY
Accession Number: edsbas.57C073DF
Database: BASE