A Platform for SpyCatcher Conjugation to Native Antibodies
| Title: | A Platform for SpyCatcher Conjugation to Native Antibodies |
|---|---|
| Authors: | Krajčovičová, Soňa; Wharton, Thomas; Driscoll, Claudia L; King, Thomas A; Howarth, Mark R; Spring, David R |
| Publisher Information: | Royal Society of Chemistry (RSC); Yusuf Hamied Department of Chemistry; //doi.org/10.1039/d5sc02286j |
| Publication Year: | 2025 |
| Collection: | Apollo - University of Cambridge Repository |
| Subject Terms: | 34 Chemical Sciences; Biotechnology; Women's Health; Breast Cancer; Cancer; Generic health relevance |
| Description: | Protein-antibody conjugates represent major advancements in targeted therapeutics. However, platforms enabling ‘off-the shelf’ antibody conjugation are seldom reported. The SpyTag/SpyCatcher system, known for its stable isopeptide bond formation, is widely. |
| Document Type: | article in journal/newspaper |
| File Description: | application/pdf |
| Language: | English |
| Relation: | https://www.repository.cam.ac.uk/handle/1810/384028; https://doi.org/10.17863/CAM.118179 |
| DOI: | 10.17863/CAM.118179 |
| Availability: | https://www.repository.cam.ac.uk/handle/1810/384028; https://doi.org/10.17863/CAM.118179 |
| Rights: | Attribution 4.0 International ; https://creativecommons.org/licenses/by/4.0/ |
| Accession Number: | edsbas.58C68F4F |
| Database: | BASE |