| Title: |
Explaining ethnic differentials in COVID-19 mortality: cohort study |
| Authors: |
Batty, GD; Gaye, B; Gale, CR; Hamer, M; Lassale, C |
| Source: |
American Journal of Epidemiology , Article kwab237. (2021) (In press). |
| Publication Year: |
2021 |
| Collection: |
University College London: UCL Discovery |
| Subject Terms: |
COVID-19; UK Biobank; cohort study; ethnicity |
| Description: |
Ethnic inequalities in coronavirus disease 2019 (COVID-19) hospitalizations and mortality have been widely reported but there is scant understanding of how they are embodied. The UK Biobank prospective cohort study comprises around half a million people who were aged 40-69 years at study induction between 2006 and 2010 when information on ethnic background and potential explanatory factors was captured. Study members were prospectively linked to a national mortality registry. In an analytical sample of 448,664 individuals (248,820 women), 705 deaths were ascribed to COVID-19 between 5th March, 2020 and 24th January, 2021. In age- and sex-adjusted analyses, relative to White participants, Black study members experienced around five times the risk of COVID-19 mortality (odds ratio; 95% confidence interval: 4.81; 3.28, 7.05), while there was a doubling in the South Asian group (2.05; 1.30, 3.25). Controlling for baseline comorbidities, social factors (including socioeconomic circumstances), and lifestyle indices attenuated this risk differential by 34% in Black study members (2.84; 1.91, 4.23) and 37% in South Asian individuals (1.57; 0.97, 2.55). The residual risk of COVID-19 deaths in ethnic minority groups may be ascribed to a range of unmeasured characteristics and requires further exploration. |
| Document Type: |
article in journal/newspaper |
| File Description: |
text |
| Language: |
English |
| Relation: |
https://discovery.ucl.ac.uk/id/eprint/10135662/1/kwab237.pdf; https://discovery.ucl.ac.uk/id/eprint/10135662/ |
| Availability: |
https://discovery.ucl.ac.uk/id/eprint/10135662/1/kwab237.pdf; https://discovery.ucl.ac.uk/id/eprint/10135662/ |
| Rights: |
open |
| Accession Number: |
edsbas.592654F4 |
| Database: |
BASE |