| Title: |
Ataxia‐Telangiectasia and Xeroderma Pigmentosum: No Evidence of Linkage to HLA |
| Authors: |
Hodge, Susan E.; Berkel, A. Izzet; Gatti, Richard A.; Boder, Elena; Spence, M. Anne |
| Source: |
Tissue Antigens ; volume 15, issue 3, page 313-317 ; ISSN 0001-2815 1399-0039 |
| Publisher Information: |
Wiley |
| Publication Year: |
1980 |
| Collection: |
Wiley Online Library (Open Access Articles via Crossref) |
| Description: |
Nine HLA‐typed multiplex nuclear families segregating ataxia‐telangiectasia (A‐T), an autosomal recessive disorder, were studied. Linkage analysis performed by lod scores and by a previously published sib pair method revealed no evidence for linkage between A‐T and HLA. An alternative method of linkage detection, previously applied to xeroderma pigmentosum (XP) and HLA, was reexamined and found to contain an error. As a consequence, neither of these “DNA repair disorders” appears to be linked to HLA. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1111/j.1399-0039.1980.tb00922.x |
| Availability: |
https://doi.org/10.1111/j.1399-0039.1980.tb00922.x; https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1399-0039.1980.tb00922.x; https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1399-0039.1980.tb00922.x |
| Rights: |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
| Accession Number: |
edsbas.5AA53528 |
| Database: |
BASE |