| Title: |
A “Leopard Man” Aspect on 18F-FDG PET/CT Revealing a VEXAS Syndrome |
| Authors: |
Fagart, Alexandre; Quemeneur, Thomas; Collet, Guillaume; Demailly, Franck; Rousselin, Clementine |
| Source: |
Clinical Nuclear Medicine ; volume 48, issue 1, page e33-e34 ; ISSN 1536-0229 0363-9762 |
| Publisher Information: |
Ovid Technologies (Wolters Kluwer Health) |
| Publication Year: |
2022 |
| Description: |
VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome is an adult-onset autoinflammatory disease caused by somatic UBA1 mutations first described in 2020. Most of these patients met clinical criteria for an inflammatory syndrome (relapsing polychondritis, Sweet syndrome, polyarteritis nodosa, or giant-cell arteritis) or a hematologic condition (myelodysplastic syndrome or multiple myeloma) or both. We described here an FDG PET/CT “leopard man” appearance, with abnormal marrow recruitment the findings, in a 70-year-old man diagnosed with a VEXAS syndrome. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1097/rlu.0000000000004443 |
| DOI: |
10.1097/RLU.0000000000004443 |
| Availability: |
https://doi.org/10.1097/rlu.0000000000004443; https://journals.lww.com/10.1097/RLU.0000000000004443 |
| Accession Number: |
edsbas.5ACF29B2 |
| Database: |
BASE |