| Title: |
Rosa Damascena Improved Sexual Dysfunction in Males Under Methadone Treatment – Results from a Double-Blind, Randomized, Placebo-Controlled Clinical Trial |
| Authors: |
Farnia, V.; Tatari, F.; Alikhani, M.; Shakeri, J.; Taghizadeh, M.; Ngo, V.T.; Sadeghi Bahmani, D.; Holsboer-Trachsler, E.; Brand, S. |
| Source: |
European Psychiatry ; volume 41, issue S1, page S281-S281 ; ISSN 0924-9338 1778-3585 |
| Publisher Information: |
Cambridge University Press (CUP) |
| Publication Year: |
2017 |
| Description: |
Introduction Patients with severe opioid dependency might be treated with methadone, a pure μ-opioid-receptor, with promising results. Though, as for opioids, side effects are high, and among those, sexual dysfunction is among the most disturbing side effects. Aims Investigating the influence of Rosa Damascena oil to improve sexual dysfunction among male methadone users. Methods A total of 60 male patients (mean age: 30 years) with diagnosed opioid dependence and currently under treatment of methadone were randomly assigned either to the verum (Rosa Damascenca oil drops) or placebo condition. At baseline, and four and eight weeks later, patients completed self-rating questionnaires covering sexual dysfunction and happiness. Results Over time sexual dysfunction decreased and happiness increased in the verum, but not in the placebo condition. Conclusions Results from this double blind, randomized, and placebo-controlled clinical trial showed that Rosa Damascena oil improved sexual dysfunction and happiness among male opioid addicts while under substitution treatment with methadone. Disclosure of interest The authors have not supplied their declaration of competing interest. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1016/j.eurpsy.2017.02.129 |
| Availability: |
https://doi.org/10.1016/j.eurpsy.2017.02.129; https://api.elsevier.com/content/article/PII:S0924933817324008?httpAccept=text/xml; https://api.elsevier.com/content/article/PII:S0924933817324008?httpAccept=text/plain; https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0924933800201557 |
| Rights: |
https://www.cambridge.org/core/terms ; https://www.elsevier.com/tdm/userlicense/1.0/ |
| Accession Number: |
edsbas.5AD4C39C |
| Database: |
BASE |